# Patient Preference for Subcutaneous vs. Intravenous Immune Therapy

Source: https://onco.cc/trials/nct07223424/  
OnCo record `nct07223424` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial of nivolumab and pembrolizumab in colorectal cancer, run by Diwakar Davar, now recruiting.

## Summary

Patient Preference for Subcutaneous vs. Intravenous Immune Therapy is a phase 2, randomised interventional study registered as NCT07223424 by Diwakar Davar, with a registry enrolment figure of 880 participants, started 2025-11-04 and due to reach its primary completion in 2030-11-30. Interventions recorded: nivolumab; pembrolizumab. Conditions listed: Renal Cell Carcinoma; Non Small Cell Lung Cancer; Melanoma; Colo-rectal Cancer (dMMR/MSI-H CRC); Hepatocellular Carcinoma; Ulcerative Colitis; Esophageal Cancer; Squamous Cell Carcinoma; Gastric/GEJ; Cervical Cancer; Gastro-Esophageal Adenocarcinoma; Esophageal Adenocarcinoma. Primary outcome: Preference for Subcutaneous Nivolumab Treatment; Preference for Subcutaneous Pembrolizumab Treatment. Sites: United States. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-24
- Also known as: PSI-Immune
- Tags: ctgov-ingest; colorectal-deep-dive
- Registry id: NCT07223424
- Phase: 2
- Setting: Patient Preference for Subcutaneous vs. Intravenous Immune Therapy (PSI-Immune)
- Sponsor: Diwakar Davar
- Enrolled: 880

## Sources

- ClinicalTrials.gov NCT07223424: https://clinicaltrials.gov/study/NCT07223424

## Connected records

- cancers: [Mismatch-repair deficient (MSI-high) colorectal cancer](https://onco.cc/cancers/msi-high-colorectal/), [Rectal cancer](https://onco.cc/cancers/rectal-cancer/)
- technologies: [Immune checkpoint inhibitors](https://onco.cc/technologies/checkpoint-inhibitor/)
- drugs: [Nivolumab](https://onco.cc/drugs/nivolumab/), [Pembrolizumab](https://onco.cc/drugs/pembrolizumab/)
- terms: [Colorectal cancer trials open today (registry snapshot)](https://onco.cc/terms/colorectal-trials-open-today/)

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JSON: https://onco.cc/api/v1/entities/nct07223424.json