# Effect of Infusion Timing on Pathologic Response to Neoadjuvant Immunotherapy in Resectable Non-Small Cell Lung Cancer

Source: https://onco.cc/trials/nct07251582/  
OnCo record `nct07251582` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 3 trial in lung cancer, run by Hunan Province Tumor Hospital, now recruiting.

## Summary

Effect of Infusion Timing on Pathologic Response to Neoadjuvant Immunotherapy in Resectable Non-Small Cell Lung Cancer is a phase 3, randomised interventional study registered as NCT07251582 by Hunan Province Tumor Hospital, with a registry enrolment figure of 186 participants, started 2026-08-12 and due to reach its primary completion in 2028-10-31. Interventions recorded: Time of Day-based Assignment for Infusion of Immune Checkpoint Inhibitor (e.g., toripalimab, or pembrolizumab) + platinum-based chemotherapy. Conditions listed: Resectable Stage II-III Non-Small Cell Lung Cancer (NSCLC). Primary outcome: Pathological Complete Response (pCR) rate. Lung eligibility wording from the registry: "Histologically or cytologically confirmed diagnosis of resectable stage II to III non-small cell lung cancer (NSCLC)". Sites: China. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-25
- Also known as: LungTime-C02
- Tags: ctgov-ingest; lung-deep-dive
- Registry id: NCT07251582
- Phase: 3
- Setting: A Prospective Study on the Effect of Infusion Timing of Immune Checkpoint Inhibitors on Pathologic Response in Patients With Resectable Stage II-III Non-Small Cell Lung Cancer Undergoing Neoadjuvant Therapy
- Sponsor: Hunan Province Tumor Hospital
- Enrolled: 186

## Sources

- ClinicalTrials.gov NCT07251582: https://clinicaltrials.gov/study/NCT07251582

## Connected records

- cancers: [Resectable stage I to III non-small-cell lung cancer](https://onco.cc/cancers/resectable-nsclc/)
- terms: [Lung cancer trials open today (registry snapshot)](https://onco.cc/terms/lung-trials-open-today/)

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JSON: https://onco.cc/api/v1/entities/nct07251582.json