# A Single-arm Clinical Study Evaluating Pirfenidone and Sintilimab in Combination With Standard Neoadjuvant Chemotherapy for Colorectal Cancer Patients With Peri

Source: https://onco.cc/trials/nct07268677/  
OnCo record `nct07268677` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial of sintilimab in colorectal cancer, run by Guoxiang Cai, not yet recruiting.

## Summary

A Single-arm Clinical Study Evaluating Pirfenidone and Sintilimab in Combination With Standard Neoadjuvant Chemotherapy for Colorectal Cancer Patients With Peritoneal Metastasis. is a phase 2, interventional study registered as NCT07268677 by Guoxiang Cai, with a registry enrolment figure of 30 participants, started 2025-12-01 and due to reach its primary completion in 2026-12-01. Interventions recorded: pirfenidone plus sintilimab combined with standard neoadjuvant chemotherapy. Conditions listed: Colorectal Cancer. Primary outcome: ORR. Colorectal eligibility wording from the registry: "Radiologically (CT/MRI/PET-CT/FAPI-PET) or pathologically confirmed peritoneal metastasis from colorectal cancer;". No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: planned
- Last checked: 2026-09-24
- Tags: ctgov-ingest; colorectal-deep-dive
- Registry id: NCT07268677
- Phase: 2
- Setting: A Single-arm Clinical Trial of Pirfenidone Plus Sintilimab Combined With Standard Neoadjuvant Chemotherapy for Patients With Colorectal Cancer Peritoneal Metastasis
- Sponsor: Guoxiang Cai
- Enrolled: 30

## Sources

- ClinicalTrials.gov NCT07268677: https://clinicaltrials.gov/study/NCT07268677

## Connected records

- cancers: [Colon cancer (adenocarcinoma of the colon)](https://onco.cc/cancers/colon-cancer/), [Rectal cancer](https://onco.cc/cancers/rectal-cancer/)
- technologies: [Immune checkpoint inhibitors](https://onco.cc/technologies/checkpoint-inhibitor/)
- drugs: [Sintilimab](https://onco.cc/drugs/sintilimab/)
- terms: [Colorectal cancer trials open today (registry snapshot)](https://onco.cc/terms/colorectal-trials-open-today/)

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