# A Phase II Clinical Study to Evaluate the Safety, Efficacy, Pharmacokinetics/Pharmacodynamics of JSKN033 in Patients With Advanced Non-Small Cell Lung Cancer

Source: https://onco.cc/trials/nct07283198/  
OnCo record `nct07283198` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial in lung cancer, run by Jiangsu Alphamab Biopharmaceuticals Co., Ltd, not yet recruiting.

## Summary

A Phase II Clinical Study to Evaluate the Safety, Efficacy, Pharmacokinetics/Pharmacodynamics of JSKN033 in Patients With Advanced Non-Small Cell Lung Cancer is a phase 2, interventional study registered as NCT07283198 by Jiangsu Alphamab Biopharmaceuticals Co., Ltd, with a registry enrolment figure of 160 participants, started 2025-12-10 and due to reach its primary completion in 2027-08-30. Interventions recorded: JSKN033 Injection. Conditions listed: Non Small Cell Lung Cancer (NSCLC). Primary outcome: Number and Severity of Treatment-emergent Adverse Events (TEAEs); Objective response rate (ORR). Lung eligibility wording from the registry: "Histologically or cytologically confirmed locally advanced or metastatic NSCLC (per AJCC 8th Edition Lung Cancer TNM Staging) that is not eligible for curative surgery and/or curative radiotherapy". No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: planned
- Last checked: 2026-09-25
- Tags: ctgov-ingest; lung-deep-dive
- Registry id: NCT07283198
- Phase: 2
- Setting: A Phase II Clinical Study to Evaluate the Safety, Efficacy, Pharmacokinetics/Pharmacodynamics of JSKN033 in Patients With Advanced Non-Small Cell Lung Cancer
- Sponsor: Jiangsu Alphamab Biopharmaceuticals Co., Ltd
- Enrolled: 160

## Sources

- ClinicalTrials.gov NCT07283198: https://clinicaltrials.gov/study/NCT07283198

## Connected records

- cancers: [Non-small-cell lung cancer](https://onco.cc/cancers/nsclc/)
- companies: [Alphamab Oncology](https://onco.cc/companies/alphamab/)
- terms: [Lung cancer trials open today (registry snapshot)](https://onco.cc/terms/lung-trials-open-today/)

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