# A Phase II Study Evaluating BMS-986504 in MTAP-deleted Pancreatic Cancer

Source: https://onco.cc/trials/nct07283705/  
OnCo record `nct07283705` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial of navlimetostat, gemcitabine, nab-paclitaxel and fOLFIRINOX / mFOLFIRINOX in pancreatic cancer, run by M.D. Anderson Cancer Center, now recruiting.

## Summary

A Phase II Study Evaluating BMS-986504 in MTAP-deleted Pancreatic Cancer is a phase 2, interventional study registered as NCT07283705 by M.D. Anderson Cancer Center, with a registry enrolment figure of 60 participants, started 2026-04-09 and due to reach its primary completion in 2029-10-01. Interventions recorded: BMS-986504; Gemcitabine; Nab-paclitaxel; mFOLFIRINOX. Conditions listed: Phase 2 Study; BMS-986504; MTAP-deleted Pancreatic Cancer. Primary outcome: Safety and adverse events (AEs). Pancreatic eligibility wording from the registry: "* Histologically or cytologically confirmed pancreatic ductal adenocarcinoma (PDAC)". Sites: United States. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-24
- Tags: ctgov-ingest; pancreatic-deep-dive
- Registry id: NCT07283705
- Phase: 2
- Setting: A Phase II Study Evaluating BMS-986504 in MTAP-deleted Pancreatic Cancer
- Sponsor: M.D. Anderson Cancer Center
- Enrolled: 60

## Sources

- ClinicalTrials.gov NCT07283705: https://clinicaltrials.gov/study/NCT07283705

## Connected records

- cancers: [Pancreatic ductal adenocarcinoma](https://onco.cc/cancers/pancreatic/)
- technologies: [Cytotoxic chemotherapy](https://onco.cc/technologies/cytotoxic-chemotherapy/), [Platinum agents](https://onco.cc/technologies/platinum/), [Topoisomerase-I inhibitors (and ADC payloads)](https://onco.cc/technologies/topoisomerase-inhibitors/)
- drugs: [FOLFIRINOX / mFOLFIRINOX](https://onco.cc/drugs/folfirinox/), [Gemcitabine](https://onco.cc/drugs/gemcitabine/), [Nab-paclitaxel](https://onco.cc/drugs/nab-paclitaxel/), [Navlimetostat](https://onco.cc/drugs/navlimetostat/)
- terms: [Pancreatic cancer trials open today (registry snapshot and UK sites)](https://onco.cc/terms/pancreatic-trials-open-today/)

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