# TTFields and Chemotherapy in Metastatic Pancreatic Adenocarcinoma (mPDAC)

Source: https://onco.cc/trials/nct07284277/  
OnCo record `nct07284277` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 1/2 trial in pancreatic cancer, run by Clinica Universidad de Navarra, Universidad de Navarra, now recruiting.

## Summary

TTFields and Chemotherapy in Metastatic Pancreatic Adenocarcinoma (mPDAC) is a phase 1/2, interventional study registered as NCT07284277 by Clinica Universidad de Navarra, Universidad de Navarra, with a registry enrolment figure of 30 participants, started 2025-10-14 and due to reach its primary completion in 2027-03. Interventions recorded: TTFields concomitant with modFOLFIRINOX. Conditions listed: Pancreatic Adenocarcinoma Metastatic; Pancreatic Ductal Adenocarcinoma. Primary outcome: Toxicity profile in patients with mPDAC treated at 1L with TTFields concomitantly with modFOLFIRINOX. Pancreatic eligibility wording from the registry: "Histological/cytological diagnosis of pancreatic adenocarcinoma". Sites: Spain. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-24
- Tags: ctgov-ingest; pancreatic-deep-dive
- Registry id: NCT07284277
- Phase: 1/2
- Setting: Phase Ib-II, Non-randomized, Open-label Study of Tumor Treating Fields (TTFields, 150 kHz) Concomitant With modFOLFIRINOX for Front-line Treatment of Metastatic Pancreatic Adenocarcinoma (NOVOFFOX)
- Sponsor: Clinica Universidad de Navarra, Universidad de Navarra
- Enrolled: 30

## Sources

- ClinicalTrials.gov NCT07284277: https://clinicaltrials.gov/study/NCT07284277

## Connected records

- cancers: [Metastatic pancreatic ductal adenocarcinoma](https://onco.cc/cancers/metastatic-pdac/)
- technologies: [Tumour treating fields (TTFields)](https://onco.cc/technologies/ttfields/)
- terms: [Pancreatic cancer trials open today (registry snapshot and UK sites)](https://onco.cc/terms/pancreatic-trials-open-today/)

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