# Liver-directed Chemotherapy After Surgery of Liver Metastases of Colorectal Cancer in Patients With High Risk of Recurrence of Their Disease

Source: https://onco.cc/trials/nct07284394/  
OnCo record `nct07284394` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 3 trial in colorectal cancer, run by UNICANCER, not yet recruiting.

## Summary

Liver-directed Chemotherapy After Surgery of Liver Metastases of Colorectal Cancer in Patients With High Risk of Recurrence of Their Disease is a phase 3, randomised interventional study registered as NCT07284394 by UNICANCER, with a registry enrolment figure of 272 participants, started 2026-07 and due to reach its primary completion in 2031-01. Interventions recorded: Arterial catheter infusion chemotherapy; IV Chemotherapy (Regimen 1). Conditions listed: Colorectal Adenocarcinoma Metastatic in the Liver; Colorectal Cancer. Primary outcome: Recurrence-free survival (RFS). No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: planned
- Last checked: 2026-09-24
- Also known as: PACHA-02
- Tags: ctgov-ingest; colorectal-deep-dive
- Registry id: NCT07284394
- Phase: 3
- Setting: Postoperative Hepatic Arterial Chemotherapy After Resection of Colorectal Liver Metastases in Patients at High Risk of Recurrence
- Sponsor: UNICANCER
- Enrolled: 272

## Sources

- ClinicalTrials.gov NCT07284394: https://clinicaltrials.gov/study/NCT07284394

## Connected records

- cancers: [Colon cancer (adenocarcinoma of the colon)](https://onco.cc/cancers/colon-cancer/), [Rectal cancer](https://onco.cc/cancers/rectal-cancer/)
- companies: [UNICANCER](https://onco.cc/companies/unicancer/)
- terms: [Colorectal cancer trials open today (registry snapshot)](https://onco.cc/terms/colorectal-trials-open-today/)

---
JSON: https://onco.cc/api/v1/entities/nct07284394.json