# SCRT VS LCRT Followed by PD-L1 Inhibitor Plus CAPEOX as TNT in Patients With LARC

Source: https://onco.cc/trials/nct07284992/  
OnCo record `nct07284992` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial in colorectal cancer, run by Shandong Provincial Hospital, now recruiting.

## Summary

SCRT VS LCRT Followed by PD-L1 Inhibitor Plus CAPEOX as TNT in Patients With LARC is a phase 2, randomised interventional study registered as NCT07284992 by Shandong Provincial Hospital, with a registry enrolment figure of 208 participants, started 2025-09-12 and due to reach its primary completion in 2028-11-30. Interventions recorded: short-term radiotherapy combined with Adebrelimab and capox; long-term radiotherapy combined with Adebrelimab and capox. Conditions listed: Rectal Cancer; Advanced Stage Colorectal Cancer; Radiotherapy. Primary outcome: CR rate. Colorectal eligibility wording from the registry: "Patients diagnosed as rectal adenocarcinoma by primary biopsy and histopathological examination;". Sites: China. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-24
- Tags: ctgov-ingest; colorectal-deep-dive
- Registry id: NCT07284992
- Phase: 2
- Setting: Total Neoadjuvant Treatment With Short-course Radiotherapy Versus Long-course Radiotherapy Followed by PD-L1 Inhibitor Plus Capecitabine-Oxaliplatin in Patients With Locally Advanced Rectal Cancer: a Multi-centres, Open-label, Phase 2, Randomized Controlled Trial
- Sponsor: Shandong Provincial Hospital
- Enrolled: 208

## Sources

- ClinicalTrials.gov NCT07284992: https://clinicaltrials.gov/study/NCT07284992

## Connected records

- cancers: [Rectal cancer](https://onco.cc/cancers/rectal-cancer/)
- technologies: [IMRT / IGRT (modern external beam)](https://onco.cc/technologies/imrt-igrt/)
- terms: [Colorectal cancer trials open today (registry snapshot)](https://onco.cc/terms/colorectal-trials-open-today/)

---
JSON: https://onco.cc/api/v1/entities/nct07284992.json