# Functional Lung Avoidance Planning Guided by Lung Perfusion PET/CT Versus Anatomical Planning for Lung Stereotactic Body Radiotherapy

Source: https://onco.cc/trials/nct07289646/  
OnCo record `nct07289646` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 3 trial in lung cancer, run by University Hospital, Brest, not yet recruiting.

## Summary

Functional Lung Avoidance Planning Guided by Lung Perfusion PET/CT Versus Anatomical Planning for Lung Stereotactic Body Radiotherapy is a phase 3, randomised interventional study registered as NCT07289646 by University Hospital, Brest, with a registry enrolment figure of 418 participants, started 2026-01-15 and due to reach its primary completion in 2029-01-31. Interventions recorded: Conventional anatomical planning radiotherapy; Functional Lung avoidance planning. Conditions listed: Stereotactic Body Radiotherapy; 68Ga-MAA; Lung Cancer (Diagnosis). Primary outcome: To determine whether a functional planning guided by lung perfusion PET/CT imaging is superior to a conventional anatomical planning with regards to the occurrence of grade 2 or higher lung toxicity during the year following lung SBRT.. Lung eligibility wording from the registry: "* Patients aged \> 18 years planned to be treated in the radiotherapy department of the participating centers with SBRT for primary or secondary lung tumors will be eligible to participate into the study". Sites: France. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: planned
- Last checked: 2026-09-25
- Also known as: Pegasus 2
- Tags: ctgov-ingest; lung-deep-dive
- Registry id: NCT07289646
- Phase: 3
- Setting: Functional Lung Avoidance Planning Guided by Lung Perfusion PET/CT Versus Anatomical Planning for Lung Stereotactic Body Radiotherapy
- Sponsor: University Hospital, Brest
- Enrolled: 418

## Sources

- ClinicalTrials.gov NCT07289646: https://clinicaltrials.gov/study/NCT07289646

## Connected records

- cancers: [Lung cancer (all types)](https://onco.cc/cancers/lung-cancer/)
- technologies: [SBRT / SABR (stereotactic radiotherapy)](https://onco.cc/technologies/sbrt/)
- terms: [Lung cancer trials open today (registry snapshot)](https://onco.cc/terms/lung-trials-open-today/)

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