# SIB-RT Combined With CAPOX and PD-1 for High-Risk Rectal Cancer

Source: https://onco.cc/trials/nct07297030/  
OnCo record `nct07297030` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial of cAPOX (capecitabine, oxaliplatin) in colorectal cancer, run by Sun Yat-sen University, not yet recruiting.

## Summary

SIB-RT Combined With CAPOX and PD-1 for High-Risk Rectal Cancer is a phase 2, interventional study registered as NCT07297030 by Sun Yat-sen University, with a registry enrolment figure of 37 participants, started 2025-12-20 and due to reach its primary completion in 2026-05-31. Interventions recorded: SIB-SCRT; CAPOX; Immunotherapy. Conditions listed: Rectal Cancer. Primary outcome: The Complete Response (CR) rate. Colorectal eligibility wording from the registry: "* Histologically confirmed diagnosis of rectal adenocarcinoma". Sites: China. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: planned
- Last checked: 2026-09-24
- Tags: ctgov-ingest; colorectal-deep-dive
- Registry id: NCT07297030
- Phase: 2
- Setting: A Prospective Single-Arm Phase II Clinical Study of Neoadjuvant Short-Course Radiotherapy With Simultaneous Integrated Boost Combined With Capecitabine-Oxaliplatin and PD-1 Inhibitor Therapy in High-Risk Locally Advanced Rectal Cancer
- Sponsor: Sun Yat-sen University
- Enrolled: 37

## Sources

- ClinicalTrials.gov NCT07297030: https://clinicaltrials.gov/study/NCT07297030

## Connected records

- cancers: [Rectal cancer](https://onco.cc/cancers/rectal-cancer/)
- technologies: [Cytotoxic chemotherapy](https://onco.cc/technologies/cytotoxic-chemotherapy/), [IMRT / IGRT (modern external beam)](https://onco.cc/technologies/imrt-igrt/), [Platinum agents](https://onco.cc/technologies/platinum/)
- drugs: [CAPOX (capecitabine, oxaliplatin)](https://onco.cc/drugs/capox/)
- terms: [Colorectal cancer trials open today (registry snapshot)](https://onco.cc/terms/colorectal-trials-open-today/)

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