# Gemcitabine and Nab-Paclitaxel Combined With Iparomlimab and Tuvorilimab for Advanced Gallbladder Cancer

Source: https://onco.cc/trials/nct07310069/  
OnCo record `nct07310069` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial of gemcitabine and nab-paclitaxel in gallbladder cancer, run by Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, now recruiting.

## Summary

Gemcitabine and Nab-Paclitaxel Combined With Iparomlimab and Tuvorilimab for Advanced Gallbladder Cancer is a phase 2 interventional study registered as NCT07310069 by Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, with a registry enrolment figure of 44 participants, started 2025-05-01 and due to reach its primary completion in 2027-05-01. Interventions recorded: Treatment :Gemcitabine plus Nab-Paclitaxel (AG regimen) in combination with Iparomlimab and Tuvorili. Conditions listed: Gallbladder Cancer Unresectable. Sites: China. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-24
- Also known as: TRANSFORM-GBC
- Tags: ctgov-ingest; gallbladder-deep-dive
- Registry id: NCT07310069
- Phase: 2
- Setting: A Phase II, Single-Arm, Multicenter Study of Gemcitabine and Nab-Paclitaxel in Combination With Iparomlimab and Tuvorilimab in Patients With Advanced Gallbladder Cancer
- Sponsor: Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
- Enrolled: 44

## Sources

- ClinicalTrials.gov NCT07310069: https://clinicaltrials.gov/study/NCT07310069

## Connected records

- cancers: [Gallbladder cancer](https://onco.cc/cancers/gallbladder/)
- technologies: [Cytotoxic chemotherapy](https://onco.cc/technologies/cytotoxic-chemotherapy/)
- drugs: [Gemcitabine](https://onco.cc/drugs/gemcitabine/), [Nab-paclitaxel](https://onco.cc/drugs/nab-paclitaxel/)
- terms: [Gallbladder cancer in biliary tract cancer trials (eligibility and subgroups)](https://onco.cc/terms/gallbladder-cancer-in-biliary-trials/)

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