# LDRT Combined With Pucotenlimab and Standard Therapy for Advanced Pancreatic Cancer: A Single-Arm Study

Source: https://onco.cc/trials/nct07312422/  
OnCo record `nct07312422` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 1/2 trial of pucotenlimab and gemcitabine + nab-paclitaxel in pancreatic cancer, run by Zhejiang Provincial People's Hospital, now recruiting.

## Summary

LDRT Combined With Pucotenlimab and Standard Therapy for Advanced Pancreatic Cancer: A Single-Arm Study is a phase 1/2, interventional study registered as NCT07312422 by Zhejiang Provincial People's Hospital, with a registry enrolment figure of 10 participants, started 2025-09-30 and due to reach its primary completion in 2026-04-30. Interventions recorded: Low-dose Radiotherapy; Pucotenlimab; AG regimen; FOLFIRINOX regimen. Conditions listed: Pancreatic Cancer; PD-L1; PD-1 Inhibitor; LDRT; Proterizumab. Primary outcome: ORR. Pancreatic eligibility wording from the registry: "* Patients with histologically or cytologically confirmed pancreatic malignancy;". Sites: China. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-24
- Tags: ctgov-ingest; pancreatic-deep-dive
- Registry id: NCT07312422
- Phase: 1/2
- Setting: An Open-label, Single-center, Single-arm Study to Evaluate the Efficacy and Safety of Low-dose Radiation Therapy Combined With Pultelimab and Standard Treatment in Patients With Advanced Pancreatic Cancer
- Sponsor: Zhejiang Provincial People's Hospital
- Enrolled: 10

## Sources

- ClinicalTrials.gov NCT07312422: https://clinicaltrials.gov/study/NCT07312422

## Connected records

- cancers: [Metastatic pancreatic ductal adenocarcinoma](https://onco.cc/cancers/metastatic-pdac/)
- technologies: [Cytotoxic chemotherapy](https://onco.cc/technologies/cytotoxic-chemotherapy/), [IMRT / IGRT (modern external beam)](https://onco.cc/technologies/imrt-igrt/)
- drugs: [Gemcitabine + nab-paclitaxel](https://onco.cc/drugs/gemcitabine-nab-paclitaxel/), [Pucotenlimab](https://onco.cc/drugs/pucotenlimab/)
- terms: [Pancreatic cancer trials open today (registry snapshot and UK sites)](https://onco.cc/terms/pancreatic-trials-open-today/)

---
JSON: https://onco.cc/api/v1/entities/nct07312422.json