# 125I Seed Implantation Plus Systemic Therapy for Oligoprogressive NSCLC or Colorectal Cancer

Source: https://onco.cc/trials/nct07333651/  
OnCo record `nct07333651` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial in colorectal cancer, run by Li Min, not yet recruiting.

## Summary

125I Seed Implantation Plus Systemic Therapy for Oligoprogressive NSCLC or Colorectal Cancer is a phase 2, randomised interventional study registered as NCT07333651 by Li Min, with a registry enrolment figure of 90 participants, started 2026-01 and due to reach its primary completion in 2027-01-01. Interventions recorded: Standard-of-Care Systemic Therapy; 125I Seed Implantation. Conditions listed: Oligometastatic Disease. Primary outcome: Progression-Free Survival (PFS). Colorectal eligibility wording from the registry: "* Histologically or cytologically confirmed metastatic non-small cell lung cancer (NSCLC) or colorectal cancer (CRC)". Sites: China. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: planned
- Last checked: 2026-09-24
- Tags: ctgov-ingest; colorectal-deep-dive
- Registry id: NCT07333651
- Phase: 2
- Setting: Standard-of-Care Systemic Therapy With or Without Image-Guided 125I Seed Implantation in Patients With Oligoprogressive Metastatic Non-Small Cell Lung Cancer or Colorectal Cancer: An Open-Label, Randomized, Controlled Phase 2 Study
- Sponsor: Li Min
- Enrolled: 90

## Sources

- ClinicalTrials.gov NCT07333651: https://clinicaltrials.gov/study/NCT07333651

## Connected records

- cancers: [Colon cancer (adenocarcinoma of the colon)](https://onco.cc/cancers/colon-cancer/), [Rectal cancer](https://onco.cc/cancers/rectal-cancer/)
- terms: [Colorectal cancer trials open today (registry snapshot)](https://onco.cc/terms/colorectal-trials-open-today/)

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JSON: https://onco.cc/api/v1/entities/nct07333651.json