# Neoadjuvant Chemotherapy Combined With Sintilimab and Bevacizumab for TNBC (NEOTORCH-BREAST07)

Source: https://onco.cc/trials/nct07351487/  
OnCo record `nct07351487` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial of sintilimab and bevacizumab in triple-negative breast cancer, run by First Affiliated Hospital of Zhejiang University, now recruiting.

## Summary

Neoadjuvant Chemotherapy Combined With Sintilimab and Bevacizumab for TNBC (NEOTORCH-BREAST07) is a phase 2, interventional study registered as NCT07351487 by First Affiliated Hospital of Zhejiang University, with a registry enrolment figure of 37 participants, started 2025-09-25 and due to reach its primary completion in 2028-09-25. Interventions recorded: Neoadjuvant chemotherapy combined with Sintilimab and Bevacizumab. Conditions listed: TNBC - Triple-Negative Breast Cancer. Triple-negative eligibility wording from the registry: "Alternatively, if ER and PR expression is less than 10% and HER2 receptor is negative, it is also classified as TNBC;". Sites: China. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-24
- Tags: ctgov-ingest; tnbc-deep-dive
- Registry id: NCT07351487
- Phase: 2
- Setting: Neoadjuvant Chemotherapy Combined With Sintilimab and Bevacizumab for Triple Negative Breast Cancer:A Prospective, Single-Arm, Multicenter Clinical Study (NEOTORCII-BREASTO7)
- Sponsor: First Affiliated Hospital of Zhejiang University
- Enrolled: 37

## Sources

- ClinicalTrials.gov NCT07351487: https://clinicaltrials.gov/study/NCT07351487

## Connected records

- cancers: [Early triple-negative breast cancer](https://onco.cc/cancers/tnbc-early/)
- technologies: [Immune checkpoint inhibitors](https://onco.cc/technologies/checkpoint-inhibitor/)
- drugs: [Bevacizumab](https://onco.cc/drugs/bevacizumab/), [Sintilimab](https://onco.cc/drugs/sintilimab/)
- terms: [Triple-negative breast cancer trials open today (registry snapshot and UK sites)](https://onco.cc/terms/tnbc-trials-open-today/)

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