# A Study of FG-M108+Chemotherapy vs Placebo+Chemotherapy in Claudin18.2-positive Pancreatic Cancer

Source: https://onco.cc/trials/nct07383922/  
OnCo record `nct07383922` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 3 trial of nab-paclitaxel and gemcitabine in pancreatic cancer, run by FutureGen Biopharmaceutical (Beijing) Co., Ltd, not yet recruiting.

## Summary

A Study of FG-M108+Chemotherapy vs Placebo+Chemotherapy in Claudin18.2-positive Pancreatic Cancer is a phase 3, randomised interventional study registered as NCT07383922 by FutureGen Biopharmaceutical (Beijing) Co., Ltd, with a registry enrolment figure of 524 participants, started 2026-02-28 and due to reach its primary completion in 2030-06-30. Interventions recorded: FG-M108; nab paclitaxel; Gemcitabine (GEM); Placebo for FG-M108. Conditions listed: Pancreatic Cancer. Primary outcome: Overall Survival (OS). Pancreatic eligibility wording from the registry: "* Histologically or cytologically confirmed unresectable locally advanced or metastatic pancreatic ductal adenocarcinoma, without prior systemic therapy; or for subjects who have received prior neoadjuvant/adjuvant chemotherapy, the time from the last treatment to disease recurrence is \>6 months;". Sites: China. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: planned
- Last checked: 2026-09-24
- Tags: ctgov-ingest; pancreatic-deep-dive
- Registry id: NCT07383922
- Phase: 3
- Setting: A Randomized, Double-blind, Placebo-controlled Phase 3 Study Comparing the Efficacy and Safety of FG-M108 Versus Placebo Combined With Standard Chemotherapy in First-line Treatment of Patients With Claudin18.2-Positive Advanced Pancreatic Cancer
- Sponsor: FutureGen Biopharmaceutical (Beijing) Co., Ltd
- Enrolled: 524

## Sources

- ClinicalTrials.gov NCT07383922: https://clinicaltrials.gov/study/NCT07383922

## Connected records

- cancers: [Locally advanced unresectable pancreatic ductal adenocarcinoma](https://onco.cc/cancers/locally-advanced-pdac/), [Metastatic pancreatic ductal adenocarcinoma](https://onco.cc/cancers/metastatic-pdac/)
- technologies: [Cytotoxic chemotherapy](https://onco.cc/technologies/cytotoxic-chemotherapy/)
- drugs: [Gemcitabine](https://onco.cc/drugs/gemcitabine/), [Nab-paclitaxel](https://onco.cc/drugs/nab-paclitaxel/)
- terms: [Pancreatic cancer trials open today (registry snapshot and UK sites)](https://onco.cc/terms/pancreatic-trials-open-today/)

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