# Short-Course Radiotherapy With Tumor-Draining Lymph Node Preservation Followed by PD-1 Inhibitors in pMMR/MSS Stage II-III Rectal Cancer

Source: https://onco.cc/trials/nct07394192/  
OnCo record `nct07394192` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial in colorectal cancer, run by Peking University Cancer Hospital & Institute, not yet recruiting.

## Summary

Short-Course Radiotherapy With Tumor-Draining Lymph Node Preservation Followed by PD-1 Inhibitors in pMMR/MSS Stage II-III Rectal Cancer is a phase 2, interventional study registered as NCT07394192 by Peking University Cancer Hospital & Institute, with a registry enrolment figure of 44 participants, started 2026-02-01 and due to reach its primary completion in 2028-12-31. Interventions recorded: short-course radiotherapy that preserves tumor-draining lymph nodes. Conditions listed: Rectal Cancer; Radiotherapy; PD-1 Inhibitor. Primary outcome: pathologic complete response rate. Colorectal eligibility wording from the registry: "* Fibrocolonoscopy or digital rectal examination indicates that the distal border of the lesion is located 5-10 cm from the anal verge". No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: planned
- Last checked: 2026-09-24
- Also known as: PKUCH- R11
- Tags: ctgov-ingest; colorectal-deep-dive
- Registry id: NCT07394192
- Phase: 2
- Setting: Exploratory Study on the Efficacy and Safety of Short-Course Radiotherapy With Tumor-Draining Lymph Node Preservation Followed by PD-1 Inhibitors in pMMR/MSS Stage II-III Rectal Cancer
- Sponsor: Peking University Cancer Hospital & Institute
- Enrolled: 44

## Sources

- ClinicalTrials.gov NCT07394192: https://clinicaltrials.gov/study/NCT07394192

## Connected records

- cancers: [Rectal cancer](https://onco.cc/cancers/rectal-cancer/)
- technologies: [IMRT / IGRT (modern external beam)](https://onco.cc/technologies/imrt-igrt/)
- terms: [Colorectal cancer trials open today (registry snapshot)](https://onco.cc/terms/colorectal-trials-open-today/)

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JSON: https://onco.cc/api/v1/entities/nct07394192.json