# Neoadjuvant Immunotherapy and Organ-sparing Treatment in Patients With Stage I-III dMMR Colon Cancer

Source: https://onco.cc/trials/nct07409844/  
OnCo record `nct07409844` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial in colorectal cancer, run by Ismail Gögenur, not yet recruiting.

## Summary

Neoadjuvant Immunotherapy and Organ-sparing Treatment in Patients With Stage I-III dMMR Colon Cancer is a phase 2, interventional study registered as NCT07409844 by Ismail Gögenur, with a registry enrolment figure of 152 participants, started 2026-03-01 and due to reach its primary completion in 2028-03-01. Interventions recorded: 1 Cycle of Pembrolizumab; 2 Cycles of Pembrolizumab; 3 Cycles of Pembrolizumab; Additional Cycle of Pembrolizumab. Conditions listed: DMMR Colorectal Cancer; Colon Cancer Stage I; Colon Cancer Stage II/III; Pembrolizumab; Immunotherapy. Primary outcome: Proportion of patients with clinical complete response (cCR). Colorectal eligibility wording from the registry: "Clinical UICC stage I-III dMMR colon carcinoma". Sites: Denmark. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: planned
- Last checked: 2026-09-24
- Also known as: RESET C2
- Tags: ctgov-ingest; colorectal-deep-dive
- Registry id: NCT07409844
- Phase: 2
- Setting: Neoadjuvant Immunotherapy and Organ-sparing Treatment in Patients With Stage I-III dMMR Colon Cancer: A National, Multicentre, Personalised, Phase II Study (RESET C2)
- Sponsor: Ismail Gögenur
- Enrolled: 152

## Sources

- ClinicalTrials.gov NCT07409844: https://clinicaltrials.gov/study/NCT07409844

## Connected records

- cancers: [Colon cancer (adenocarcinoma of the colon)](https://onco.cc/cancers/colon-cancer/), [Mismatch-repair deficient (MSI-high) colorectal cancer](https://onco.cc/cancers/msi-high-colorectal/)
- terms: [Colorectal cancer trials open today (registry snapshot)](https://onco.cc/terms/colorectal-trials-open-today/)

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JSON: https://onco.cc/api/v1/entities/nct07409844.json