# Carbon Nanoparticle-Loaded Iron in the Treatment of Advanced Solid Tumor

Source: https://onco.cc/trials/nct07433283/  
OnCo record `nct07433283` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 1/2 trial in pancreatic cancer, run by Sichuan Enray Pharmaceutical Sciences Company, now recruiting.

## Summary

Carbon Nanoparticle-Loaded Iron in the Treatment of Advanced Solid Tumor is a phase 1/2, interventional study registered as NCT07433283 by Sichuan Enray Pharmaceutical Sciences Company, with a registry enrolment figure of 54 participants, started 2024-11-12 and due to reach its primary completion in 2026-12-31. Interventions recorded: Carbon Nanoparticle-Loaded Iron [CNSI-Fe]; Carbon Nanoparticle-Loaded Iron. Conditions listed: Tumor, Solid; Lung Cancer; Pancreas Cancer; Thyroid Cancer; Colorectal Cancer; Cervical Cancer; Vulva Cancer. Primary outcome: Incidence and severity of participants with treatment-related adverse events as assessed by CTCAE v5.0. Pancreatic eligibility wording from the registry: "Stage Ib: patients with advanced solid tumors confirmed by histology or cytology, and the current standard therapy is ineffective (disease progression after treatment or treatment is not tolerated) or there is no effective standard treatment, such as soft tissue sarcoma, refractory thyroid cancer, c". Sites: China. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-24
- Tags: ctgov-ingest; pancreatic-deep-dive
- Registry id: NCT07433283
- Phase: 1/2
- Setting: A Phase Ib/IIa Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetic Profile, and Preliminary Efficacy of Intratumoral Injection of Carbon Nanoparticle-Loaded Iron Suspension Injection [CNSI-Fe(II)] With Multiple Administrations in Subjects With Advanced Solid Tumors
- Sponsor: Sichuan Enray Pharmaceutical Sciences Company
- Enrolled: 54

## Sources

- ClinicalTrials.gov NCT07433283: https://clinicaltrials.gov/study/NCT07433283

## Connected records

- cancers: [Metastatic pancreatic ductal adenocarcinoma](https://onco.cc/cancers/metastatic-pdac/)
- terms: [Pancreatic cancer trials open today (registry snapshot and UK sites)](https://onco.cc/terms/pancreatic-trials-open-today/)

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