# Anlotinib Plus Whole-Brain Radiotherapy for Brain Metastases in SCLC Patients.

Source: https://onco.cc/trials/nct07443397/  
OnCo record `nct07443397` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 3 trial of anlotinib in lung cancer, run by Cancer Institute and Hospital, Chinese Academy of Medical Sciences, now recruiting.

## Summary

Anlotinib Plus Whole-Brain Radiotherapy for Brain Metastases in SCLC Patients. is a phase 3, randomised interventional study registered as NCT07443397 by Cancer Institute and Hospital, Chinese Academy of Medical Sciences, with a registry enrolment figure of 134 participants, started 2025-08-29 and due to reach its primary completion in 2027-08-31. Interventions recorded: Anlotinib; Whole-brain Radiotherapy. Conditions listed: Whole-Brain Radiotherapy. Primary outcome: Intracranial progression-free survival. Lung eligibility wording from the registry: "* Small cell lung cancer confirmed by pathology, with brain metastases diagnosed either at initial presentation or during treatment, and measurable disease according to RECIST criteria". Sites: China. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-25
- Tags: ctgov-ingest; lung-deep-dive
- Registry id: NCT07443397
- Phase: 3
- Setting: Anlotinib Plus Whole-Brain Radiotherapy for Brain Metastases in Small Cell Lung Cancer Patients: A Multicenter Phase III Trail.
- Sponsor: Cancer Institute and Hospital, Chinese Academy of Medical Sciences
- Enrolled: 134

## Sources

- ClinicalTrials.gov NCT07443397: https://clinicaltrials.gov/study/NCT07443397

## Connected records

- cancers: [Small-cell lung cancer](https://onco.cc/cancers/sclc/)
- technologies: [Anti-angiogenic therapy](https://onco.cc/technologies/antiangiogenic/), [IMRT / IGRT (modern external beam)](https://onco.cc/technologies/imrt-igrt/), [Small-molecule kinase inhibitors](https://onco.cc/technologies/kinase-inhibitors/)
- drugs: [Anlotinib](https://onco.cc/drugs/anlotinib/)
- terms: [Lung cancer trials open today (registry snapshot)](https://onco.cc/terms/lung-trials-open-today/)

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