# Neoadjuvant SHR-1701 Plus Chemoradiotherapy for Locally Advanced Rectal Cancer

Source: https://onco.cc/trials/nct07478731/  
OnCo record `nct07478731` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial in colorectal cancer, run by Hong Qiu, now recruiting.

## Summary

Neoadjuvant SHR-1701 Plus Chemoradiotherapy for Locally Advanced Rectal Cancer is a phase 2, interventional study registered as NCT07478731 by Hong Qiu, with a registry enrolment figure of 48 participants, started 2025-12-20 and due to reach its primary completion in 2027-12-31. Interventions recorded: SHR-1701 neoadjuvant. Conditions listed: CRC (Colorectal Cancer). Primary outcome: pCR. Colorectal eligibility wording from the registry: "3: Pathologically confirmed rectal adenocarcinoma（At least meet any of the following criteria：cT3-4、cN2、EMVI+、MRF+）". Sites: China. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-24
- Also known as: MA-CRC-II-018
- Tags: ctgov-ingest; colorectal-deep-dive
- Registry id: NCT07478731
- Phase: 2
- Setting: A Phase II, Prospective, Single Arm Study of Neoadjuvant SHR-1701 Combine With Chemoradiotherapy for Locally Advanced Rectal Cancer
- Sponsor: Hong Qiu
- Enrolled: 48

## Sources

- ClinicalTrials.gov NCT07478731: https://clinicaltrials.gov/study/NCT07478731

## Connected records

- cancers: [Rectal cancer](https://onco.cc/cancers/rectal-cancer/)
- technologies: [IMRT / IGRT (modern external beam)](https://onco.cc/technologies/imrt-igrt/)
- terms: [Colorectal cancer trials open today (registry snapshot)](https://onco.cc/terms/colorectal-trials-open-today/)

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JSON: https://onco.cc/api/v1/entities/nct07478731.json