# Cryoablation Versus Lumpectomy in Early-Stage Breast Cancer

Source: https://onco.cc/trials/nct07483996/  
OnCo record `nct07483996` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 3 trial of Thermal ablation in Breast cancer, run by Franciscus Gasthuis & Vlietland (Hospital), not yet recruiting.

## Summary

Cryoablation Versus Lumpectomy in Early-Stage Breast Cancer is a phase 3 interventional study registered as NCT07483996 by Franciscus Gasthuis & Vlietland (Hospital), with 938 participants planned, started 2026-04-01 and due to reach its primary completion in 2035-12-31. Interventions recorded: Percutaneous cryoablation, Breast-conserving surgery. Conditions recorded: Early-Stage Breast Cancer.

Linked to the technology Thermal ablation because the registry names it ("thermal ablation") among its interventions and Breast cancer among its conditions. Registry record only: no result has been read by an editor.

## Fields

- Kind: Trial
- Status: planned
- Last checked: 2026-09-22
- Tags: pipeline; ctgov-ingest
- Registry id: NCT07483996
- Phase: 3
- Setting: Cryoablation as Alternative for Lumpectomy in Early-Stage Breast Cancer: The CRYSTAL Trial
- Sponsor: Franciscus Gasthuis & Vlietland (Hospital)
- Enrolled: 938

## Sources

- ClinicalTrials.gov NCT07483996: https://clinicaltrials.gov/study/NCT07483996

## Connected records

- cancers: [Breast cancer (all types)](https://onco.cc/cancers/breast-cancer/)
- technologies: [Thermal ablation (RFA, microwave, cryo)](https://onco.cc/technologies/thermal-ablation/)

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