# Hepatic Arterial Infusion of Sodium Bicarbonate (NaHCO3) Combined With NASOX Regimen and Programmed Death-1 (PD-1) Inhibitors for Pancreatic Cancer Liver Metast

Source: https://onco.cc/trials/nct07504471/  
OnCo record `nct07504471` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial in pancreatic cancer, run by Ruijin Hospital, now recruiting.

## Summary

Hepatic Arterial Infusion of Sodium Bicarbonate (NaHCO3) Combined With NASOX Regimen and Programmed Death-1 (PD-1) Inhibitors for Pancreatic Cancer Liver Metastases is a phase 2, interventional study registered as NCT07504471 by Ruijin Hospital, with a registry enrolment figure of 50 participants, started 2026-03-23 and due to reach its primary completion in 2026-12-31. Interventions recorded: pH-NASOX-Immune Group. Conditions listed: Pancreatic Neoplasms; Hepatic Metastasis of Pancreatic Cancer. Primary outcome: Overall Survival (OS). Pancreatic eligibility wording from the registry: "* Pathologically confirmed pancreatic cancer (originating from the pancreatic ductal epithelium), with metastasis to the liver;". Sites: China. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-24
- Tags: ctgov-ingest; pancreatic-deep-dive
- Registry id: NCT07504471
- Phase: 2
- Setting: A Prospective, Single-Center, Phase II Clinical Study of Hepatic Arterial Infusion of Sodium Bicarbonate (NaHCO3) Combined With NASOX Regimen (Liposomal Irinotecan, Oxaliplatin, and S-1) Hepatic Arterial Infusion Chemotherapy (HAIC) and Intra-Arterial Programmed Death-1 (PD-1) Inhibitors for Liver Metastases From Pancreatic Cancer
- Sponsor: Ruijin Hospital
- Enrolled: 50

## Sources

- ClinicalTrials.gov NCT07504471: https://clinicaltrials.gov/study/NCT07504471

## Connected records

- cancers: [Metastatic pancreatic ductal adenocarcinoma](https://onco.cc/cancers/metastatic-pdac/)
- terms: [Pancreatic cancer trials open today (registry snapshot and UK sites)](https://onco.cc/terms/pancreatic-trials-open-today/)

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