# FMT Combined With Standard First-Line Therapy in Initially Unresectable Colorectal Cancer

Source: https://onco.cc/trials/nct07509398/  
OnCo record `nct07509398` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2/3 trial in colorectal cancer, run by Shanghai 10th People's Hospital, not yet recruiting.

## Summary

FMT Combined With Standard First-Line Therapy in Initially Unresectable Colorectal Cancer is a phase 2/3, randomised interventional study registered as NCT07509398 by Shanghai 10th People's Hospital, with a registry enrolment figure of 220 participants, started 2026-04 and due to reach its primary completion in 2027-12. Interventions recorded: Standard First-Line Therapy; FMT Combined with Standard First-Line Therapy. Conditions listed: Unresectable Colorectal Cancer; Colorectal Cancer (Locally Advanced or Metastatic). Primary outcome: Objective Response Rate. Colorectal eligibility wording from the registry: "(3) Meet the defined criteria for initially unresectable advanced metastatic colorectal cancer (mCRC) for this project". No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: planned
- Last checked: 2026-09-24
- Tags: ctgov-ingest; colorectal-deep-dive
- Registry id: NCT07509398
- Phase: 2/3
- Setting: Efficacy and Safety of Fecal Microbiota Transplantation Combined With First-Line Standard Therapy in Patients With Initially Unresectable Colorectal Cancer: A Multicenter, Open-Label, Randomized Controlled Trial
- Sponsor: Shanghai 10th People's Hospital
- Enrolled: 220

## Sources

- ClinicalTrials.gov NCT07509398: https://clinicaltrials.gov/study/NCT07509398

## Connected records

- cancers: [Colon cancer (adenocarcinoma of the colon)](https://onco.cc/cancers/colon-cancer/), [Rectal cancer](https://onco.cc/cancers/rectal-cancer/)
- terms: [Colorectal cancer trials open today (registry snapshot)](https://onco.cc/terms/colorectal-trials-open-today/)

---
JSON: https://onco.cc/api/v1/entities/nct07509398.json