# A Single-arm Phase II Clinical Study of Camrelizumab Combined With Long-course Chemoradiotherapy for Total Neoadjuvant Therapy in Locally Advanced Low pMMR/MSS

Source: https://onco.cc/trials/nct07527026/  
OnCo record `nct07527026` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial of camrelizumab in colorectal cancer, run by Chinese PLA General Hospital, now recruiting.

## Summary

A Single-arm Phase II Clinical Study of Camrelizumab Combined With Long-course Chemoradiotherapy for Total Neoadjuvant Therapy in Locally Advanced Low pMMR/MSS Rectal Cancer is a phase 2, interventional study registered as NCT07527026 by Chinese PLA General Hospital, with a registry enrolment figure of 44 participants, started 2026-02-01 and due to reach its primary completion in 2028-02-01. Interventions recorded: Camrelizumab. Conditions listed: Locally Advanced Rectal Cancer. Primary outcome: CR rate. Colorectal eligibility wording from the registry: "Histologically confirmed T3-4 and/or N+ rectal adenocarcinoma (AJCC/UICC TNM staging, 8th edition);". Sites: China. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-24
- Tags: ctgov-ingest; colorectal-deep-dive
- Registry id: NCT07527026
- Phase: 2
- Setting: A Single-arm Phase II Clinical Study of Camrelizumab Combined With Long-course Chemoradiotherapy for Total Neoadjuvant Therapy in Locally Advanced Low pMMR/MSS Rectal Cancer
- Sponsor: Chinese PLA General Hospital
- Enrolled: 44

## Sources

- ClinicalTrials.gov NCT07527026: https://clinicaltrials.gov/study/NCT07527026

## Connected records

- cancers: [Rectal cancer](https://onco.cc/cancers/rectal-cancer/)
- technologies: [Immune checkpoint inhibitors](https://onco.cc/technologies/checkpoint-inhibitor/), [IMRT / IGRT (modern external beam)](https://onco.cc/technologies/imrt-igrt/)
- drugs: [Camrelizumab](https://onco.cc/drugs/camrelizumab/)
- terms: [Colorectal cancer trials open today (registry snapshot)](https://onco.cc/terms/colorectal-trials-open-today/)

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