# Study to Assess the Efficacy and Safety of Rina-S With or Without Bevacizumab Compared to Investigator's Choice of Platinum-based Chemotherapy With or

Source: https://onco.cc/trials/nct07564141/  
OnCo record `nct07564141` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 3 trial of Rinatabart sesutecan, Bevacizumab, Carboplatin in ovarian cancer, run by Genmab, now recruiting.

## Summary

Study to Assess the Efficacy and Safety of Rina-S With or Without Bevacizumab Compared to Investigator's Choice of Platinum-based Chemotherapy With or Without Bevacizumab as Second-line Treatment in Participants With Recurrent Platinum-sensitive Ovarian Cancer is a phase 3 interventional study registered as NCT07564141 by Genmab, with 688 participants planned, started 2026-08-28 and due to reach its primary completion in 2029-12. Interventions recorded: Rina-S, Bevacizumab, Carboplatin, Gemcitabine, Paclitaxel. Conditions listed: Platinum-Sensitive Ovarian Cancer, Ovarian Cancer. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-16
- Tags: ctgov-ingest
- Registry id: NCT07564141
- Phase: 3
- Setting: A Randomized, Open-label, Phase 3 Study of Rina-S ± Bevacizumab Versus Investigator's Choice of Platinum-Based Chemotherapy ± Bevacizumab as 2L Treatment in Participants With Recurrent Platinum-Sensitive Ovarian Cancer
- Sponsor: Genmab
- Enrolled: 688

## Sources

- ClinicalTrials.gov NCT07564141: https://clinicaltrials.gov/study/NCT07564141

## Connected records

- cancers: [Ovarian cancer](https://onco.cc/cancers/ovarian/)
- drugs: [Bevacizumab](https://onco.cc/drugs/bevacizumab/), [Carboplatin](https://onco.cc/drugs/carboplatin/), [Gemcitabine](https://onco.cc/drugs/gemcitabine/), [Paclitaxel / nab-paclitaxel](https://onco.cc/drugs/paclitaxel/), [Rinatabart sesutecan](https://onco.cc/drugs/rinatabart-sesutecan/)
- companies: [Genmab](https://onco.cc/companies/genmab/)

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