# Short-Course Radiotherapy Followed by Immunotherapy Combined With Chemotherapy for Microsatellite Stable Locally Advanced Rectal Cancer: A Prospective, Randomiz

Source: https://onco.cc/trials/nct07594925/  
OnCo record `nct07594925` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial of sintilimab in colorectal cancer, run by Tianjin Medical University Cancer Institute and Hospital, now recruiting.

## Summary

Short-Course Radiotherapy Followed by Immunotherapy Combined With Chemotherapy for Microsatellite Stable Locally Advanced Rectal Cancer: A Prospective, Randomized, Controlled Phase II Clinical Trial is a phase 2, randomised interventional study registered as NCT07594925 by Tianjin Medical University Cancer Institute and Hospital, with a registry enrolment figure of 130 participants, started 2026-05-01 and due to reach its primary completion in 2029-06-01. Interventions recorded: Sintilimab; Chemotherapy Drugs; radiotherapy. Conditions listed: Rectal Cancer. Primary outcome: DFS. Colorectal eligibility wording from the registry: "The lower boundary of the lesion is ≤ 10 cm from the anal verge, confirmed by colonoscopy or digital rectal examination;". Sites: China. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-24
- Tags: ctgov-ingest; colorectal-deep-dive
- Registry id: NCT07594925
- Phase: 2
- Setting: Short-Course Radiotherapy Followed by Immunotherapy Combined With Chemotherapy for Microsatellite Stable Locally Advanced Rectal Cancer: A Prospective, Randomized, Controlled Phase II Clinical Trial
- Sponsor: Tianjin Medical University Cancer Institute and Hospital
- Enrolled: 130

## Sources

- ClinicalTrials.gov NCT07594925: https://clinicaltrials.gov/study/NCT07594925

## Connected records

- cancers: [Rectal cancer](https://onco.cc/cancers/rectal-cancer/)
- technologies: [Immune checkpoint inhibitors](https://onco.cc/technologies/checkpoint-inhibitor/), [IMRT / IGRT (modern external beam)](https://onco.cc/technologies/imrt-igrt/)
- drugs: [Sintilimab](https://onco.cc/drugs/sintilimab/)
- terms: [Colorectal cancer trials open today (registry snapshot)](https://onco.cc/terms/colorectal-trials-open-today/)

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