# PHOENIX-ECP- Extracorporeal Photopheresis for Immune-related Colitis and/or Hepatitis in Advanced Melanoma With Inadequate Response to Steroid Exposure

Source: https://onco.cc/trials/nct07619898/  
OnCo record `nct07619898` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial of Methoxsalen in Skin cancer and Melanoma, run by Therakos LLC, not yet recruiting.

## Summary

PHOENIX-ECP- Extracorporeal Photopheresis for Immune-related Colitis and/or Hepatitis in Advanced Melanoma With Inadequate Response to Steroid Exposure is a phase 2 interventional study registered as NCT07619898 by Therakos LLC, with 112 participants planned, started 2026-07 and due to reach its primary completion in 2028-12. Interventions recorded: methoxsalen, Extracorporeal photopheresis (ECP), Vedolizumab, Infliximab, Mycophenolate Mofetil (MMF), Azathioprine. Conditions recorded: Colitis, Hepatitis, Melanoma (Skin Cancer).

Linked to the drug Methoxsalen because the registry names it among its interventions and Skin cancer and Melanoma among its conditions. Registry record only: no result has been read by an editor.

## Fields

- Kind: Trial
- Status: planned
- Last checked: 2026-09-22
- Tags: pipeline; ctgov-ingest
- Registry id: NCT07619898
- Phase: 2
- Setting: PHOENIX- A Phase 2, Randomized, Controlled, Open-label, Multicenter Study to Evaluate the Efficacy and Safety/Tolerability of Extracorporeal Photopheresis (ECP) Versus Best Available Therapy (BAT) for the Treatment of Immune-related Colitis or Hepatitis With Inadequate Response to Corticosteroids in Participants With Unresectable or Metastatic Melanoma Treated With Immune Checkpoint Inhibitors (ICI)
- Sponsor: Therakos LLC
- Enrolled: 112

## Sources

- ClinicalTrials.gov NCT07619898: https://clinicaltrials.gov/study/NCT07619898

## Connected records

- cancers: [Melanoma](https://onco.cc/cancers/melanoma/), [Skin cancer (all types)](https://onco.cc/cancers/skin-cancer/)
- drugs: [Methoxsalen (extracorporeal photopheresis)](https://onco.cc/drugs/methoxsalen-ecp/)

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