# Laser Interstitial Thermal Therapy (LiTT) With Cemiplimab or Other Chemotherapy in Recurrent Glioblastomas

Source: https://onco.cc/trials/nct07620548/  
OnCo record `nct07620548` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial of Laser interstitial thermal therapy systems in Glioma & glioblastoma, run by Washington University School of Medicine, not yet recruiting.

## Summary

Laser Interstitial Thermal Therapy (LiTT) With Cemiplimab or Other Chemotherapy in Recurrent Glioblastomas is a phase 2 interventional study registered as NCT07620548 by Washington University School of Medicine, with 99 participants planned, started 2026-08-31 and due to reach its primary completion in 2031-02-28. Interventions recorded: NeuroBlate® Laser Ablation Laser Interstitial Thermal Therapy, Cemiplimab, Chemotherapy. Conditions recorded: Glioblastoma, Glioblastoma, IDH-wildtype, Glioblastoma IDH (Isocitrate Dehydrogenase) Wildtype.

Linked to the technology Laser interstitial thermal therapy systems because the registry names it ("neuroblate") among its interventions and Glioma & glioblastoma among its conditions. Registry record only: no result has been read by an editor.

## Fields

- Kind: Trial
- Status: planned
- Last checked: 2026-09-22
- Tags: pipeline; ctgov-ingest
- Registry id: NCT07620548
- Phase: 2
- Setting: A Randomized Phase II Study of the Efficacy of Laser Interstitial Thermal Therapy (LiTT) Combined With Cemiplimab Versus Physician's Choice Chemotherapy in Recurrent Glioblastomas
- Sponsor: Washington University School of Medicine
- Enrolled: 99

## Sources

- ClinicalTrials.gov NCT07620548: https://clinicaltrials.gov/study/NCT07620548

## Connected records

- cancers: [Glioma & glioblastoma](https://onco.cc/cancers/glioblastoma/)
- technologies: [Laser interstitial thermal therapy systems (NeuroBlate, Visualase)](https://onco.cc/technologies/litt-systems/)
- drugs: [Cemiplimab](https://onco.cc/drugs/cemiplimab/)

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