# KORTUC (KRC-01) Plus Radiotherapy for Organ Preservation in Rectal Cancer

Source: https://onco.cc/trials/nct07622017/  
OnCo record `nct07622017` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial of capecitabine, cAPOX (capecitabine, oxaliplatin) and fOLFOX (5-FU, leucovorin, oxaliplatin) in colorectal cancer, run by Gustave Roussy, Cancer Campus, Grand Paris, not yet recruiting.

## Summary

KORTUC (KRC-01) Plus Radiotherapy for Organ Preservation in Rectal Cancer is a phase 2, interventional study registered as NCT07622017 by Gustave Roussy, Cancer Campus, Grand Paris, with a registry enrolment figure of 24 participants, started 2026-07 and due to reach its primary completion in 2029-01. Interventions recorded: KRC-01 (KORTUC); Radiotherapy; Capecitabine; CAPOX; FOLFOX; Optionnal TME. Conditions listed: Rectal Cancer. Primary outcome: Clinical Complete Response (cCR) Rate at Week 24. Colorectal eligibility wording from the registry: "Histopathologically confirmed locally advanced rectal adenocarcinoma, stage III (high risk)". Sites: France. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: planned
- Last checked: 2026-09-24
- Also known as: K-BOOST
- Tags: ctgov-ingest; colorectal-deep-dive
- Registry id: NCT07622017
- Phase: 2
- Setting: Phase II Clinical Trial of KORTUC (KRC-01) Combined With Radiotherapy for Locally Advanced Rectal Cancer: Towards a New Organ Preservation Approach
- Sponsor: Gustave Roussy, Cancer Campus, Grand Paris
- Enrolled: 24

## Sources

- ClinicalTrials.gov NCT07622017: https://clinicaltrials.gov/study/NCT07622017

## Connected records

- cancers: [Rectal cancer](https://onco.cc/cancers/rectal-cancer/)
- technologies: [Cytotoxic chemotherapy](https://onco.cc/technologies/cytotoxic-chemotherapy/), [IMRT / IGRT (modern external beam)](https://onco.cc/technologies/imrt-igrt/), [Platinum agents](https://onco.cc/technologies/platinum/)
- drugs: [Capecitabine](https://onco.cc/drugs/capecitabine/), [CAPOX (capecitabine, oxaliplatin)](https://onco.cc/drugs/capox/), [FOLFOX (5-FU, leucovorin, oxaliplatin)](https://onco.cc/drugs/folfox/)
- terms: [Colorectal cancer trials open today (registry snapshot)](https://onco.cc/terms/colorectal-trials-open-today/)

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JSON: https://onco.cc/api/v1/entities/nct07622017.json