# A Single-arm, Multicenter Clinical Study of Fruquintinib Combined With Serplulimab and Chemotherapy as First-line Treatment for Patients With RAS/BRAF-mutated A

Source: https://onco.cc/trials/nct07622550/  
OnCo record `nct07622550` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial in colorectal cancer, run by Jiangsu Cancer Institute & Hospital, not yet recruiting.

## Summary

A Single-arm, Multicenter Clinical Study of Fruquintinib Combined With Serplulimab and Chemotherapy as First-line Treatment for Patients With RAS/BRAF-mutated Advanced Colorectal Cance is a phase 2, interventional study registered as NCT07622550 by Jiangsu Cancer Institute & Hospital, with a registry enrolment figure of 80 participants, started 2026-06-15 and due to reach its primary completion in 2027-12-15. Interventions recorded: Serplulimab+Fruquintinib+XELOX. Conditions listed: Metastatic Colorectal Cancer (CRC). Primary outcome: Investigator-assessed Progression-Free Survival（PFS）. Colorectal eligibility wording from the registry: "* Diagnosis of advanced unresectable or metastatic colorectal cancer". Sites: China. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: planned
- Last checked: 2026-09-24
- Tags: ctgov-ingest; colorectal-deep-dive
- Registry id: NCT07622550
- Phase: 2
- Setting: A Single-arm, Multicenter Clinical Study of Fruquintinib Combined With Serplulimab and Chemotherapy as First-line Treatment for Patients With RAS/BRAF-mutated Advanced Colorectal Cance
- Sponsor: Jiangsu Cancer Institute & Hospital
- Enrolled: 80

## Sources

- ClinicalTrials.gov NCT07622550: https://clinicaltrials.gov/study/NCT07622550

## Connected records

- cancers: [Colon cancer (adenocarcinoma of the colon)](https://onco.cc/cancers/colon-cancer/), [Rectal cancer](https://onco.cc/cancers/rectal-cancer/)
- terms: [Colorectal cancer trials open today (registry snapshot)](https://onco.cc/terms/colorectal-trials-open-today/)

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JSON: https://onco.cc/api/v1/entities/nct07622550.json