# A Phase-II Clinical Trial of Radiotherapy to the Coeliac Plexus to Help Pain in Advanced Pancreatic Cancer

Source: https://onco.cc/trials/nct07689955/  
OnCo record `nct07689955` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial in pancreatic cancer, run by Royal Marsden NHS Foundation Trust, not yet recruiting.

## Summary

A Phase-II Clinical Trial of Radiotherapy to the Coeliac Plexus to Help Pain in Advanced Pancreatic Cancer is a phase 2, interventional study registered as NCT07689955 by Royal Marsden NHS Foundation Trust, with a registry enrolment figure of 52 participants, started 2026-09 and due to reach its primary completion in 2029-09. Interventions recorded: IMRT. Conditions listed: Pancreatic Cancer. Primary outcome: To assess the clinical benefit of IMRT radiotherapy to the coeliac plexus in achieving a clinically meaningful reduction in participant-reported pain in participants with inoperable advanced pancreatic adenocarcinoma.. Pancreatic eligibility wording from the registry: "Pain with a BPI score ≥ 2 as a result of pancreatic adenocarcinoma, not sufficiently responding to opiate medication". No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: planned
- Last checked: 2026-09-24
- Also known as: PANCPLEX
- Tags: ctgov-ingest; pancreatic-deep-dive
- Registry id: NCT07689955
- Phase: 2
- Setting: A Multi-Centre, Single-Arm Prospective Phase II Clinical Trial of Radiotherapy to the Coeliac Plexus to Help Pain in Advanced Pancreatic Cancer
- Sponsor: Royal Marsden NHS Foundation Trust
- Enrolled: 52

## Sources

- ClinicalTrials.gov NCT07689955: https://clinicaltrials.gov/study/NCT07689955

## Connected records

- cancers: [Metastatic pancreatic ductal adenocarcinoma](https://onco.cc/cancers/metastatic-pdac/)
- technologies: [IMRT / IGRT (modern external beam)](https://onco.cc/technologies/imrt-igrt/)
- terms: [Pancreatic cancer trials open today (registry snapshot and UK sites)](https://onco.cc/terms/pancreatic-trials-open-today/)

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