# IBI343 Combined With Chemotherapy in Advanced Pancreatic Cancer

Source: https://onco.cc/trials/nct07692750/  
OnCo record `nct07692750` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 1/2 trial of IBI343, capecitabine and cAPOX (capecitabine, oxaliplatin) in pancreatic cancer, run by Zhejiang Cancer Hospital, now recruiting.

## Summary

IBI343 Combined With Chemotherapy in Advanced Pancreatic Cancer is a phase 1/2, interventional study registered as NCT07692750 by Zhejiang Cancer Hospital, with a registry enrolment figure of 56 participants, started 2025-04-30 and due to reach its primary completion in 2027-06-30. Interventions recorded: IBI343+ capecitabine; IBI343+Capecitabine+oxaliplatin. Conditions listed: Advanced Pancreatic Cancer. Primary outcome: Objective Response Rate (ORR) according to RECIST v1.1; Adverse Event, Treatment-Emergent Adverse Event, Adverse Event of Special Interest, Serious Serious Adverse EventChanges in laboratory tests, physical examinations, vital signs, etc., incidence, and correlation with experimental drugs. Sites: China. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-24
- Tags: ctgov-ingest; pancreatic-deep-dive
- Registry id: NCT07692750
- Phase: 1/2
- Setting: A Phase Ib/II Study to Evaluate the Safety, Tolerability and Efficacy of IBI343 in Combination With Chemotherapy in Subjects With Advanced Pancreatic Cancer
- Sponsor: Zhejiang Cancer Hospital
- Enrolled: 56

## Sources

- ClinicalTrials.gov NCT07692750: https://clinicaltrials.gov/study/NCT07692750

## Connected records

- cancers: [Metastatic pancreatic ductal adenocarcinoma](https://onco.cc/cancers/metastatic-pdac/)
- technologies: [Antibody-drug conjugate (ADC)](https://onco.cc/technologies/adc/), [Cytotoxic chemotherapy](https://onco.cc/technologies/cytotoxic-chemotherapy/)
- drugs: [Capecitabine](https://onco.cc/drugs/capecitabine/), [CAPOX (capecitabine, oxaliplatin)](https://onco.cc/drugs/capox/), [IBI343](https://onco.cc/drugs/ibi343/)
- terms: [Pancreatic cancer trials open today (registry snapshot and UK sites)](https://onco.cc/terms/pancreatic-trials-open-today/)

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