# Immunotheray Combined With Simvastatin and Target Therapy and Chemotharepy for Advanced Colorectal Cancer

Source: https://onco.cc/trials/nct07718490/  
OnCo record `nct07718490` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial of adebrelimab in colorectal cancer, run by The First Affiliated Hospital with Nanjing Medical University, now recruiting.

## Summary

Immunotheray Combined With Simvastatin and Target Therapy and Chemotharepy for Advanced Colorectal Cancer is a phase 2, interventional study registered as NCT07718490 by The First Affiliated Hospital with Nanjing Medical University, with a registry enrolment figure of 43 participants, started 2025-09-01 and due to reach its primary completion in 2027-12-31. Interventions recorded: Adebrelimab. Conditions listed: Metastatic Colorectal Cancer. Primary outcome: Investigator-assessed Objective Response Rate（ORR）. Colorectal eligibility wording from the registry: "Histologically or cytologically confirmed metastatic colorectal adenocarcinoma". Sites: China. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-24
- Tags: ctgov-ingest; colorectal-deep-dive
- Registry id: NCT07718490
- Phase: 2
- Setting: A Multicenter, Prospective, Phase II Exploratory Study on the First-line Treatment of MSS/ PMMR-type Advanced Colorectal Cancer With Adebrelimab Combined With Simvastatin and Targeted and Chemotherapy
- Sponsor: The First Affiliated Hospital with Nanjing Medical University
- Enrolled: 43

## Sources

- ClinicalTrials.gov NCT07718490: https://clinicaltrials.gov/study/NCT07718490

## Connected records

- cancers: [Colon cancer (adenocarcinoma of the colon)](https://onco.cc/cancers/colon-cancer/), [Rectal cancer](https://onco.cc/cancers/rectal-cancer/)
- technologies: [Immune checkpoint inhibitors](https://onco.cc/technologies/checkpoint-inhibitor/)
- drugs: [Adebrelimab](https://onco.cc/drugs/adebrelimab/)
- companies: [Jiangsu Hengrui Pharmaceuticals](https://onco.cc/companies/hengrui/)
- terms: [Colorectal cancer trials open today (registry snapshot)](https://onco.cc/terms/colorectal-trials-open-today/)

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