# A Vaccine (STEMVAC) for Improving Survival in Patients With Triple-Negative Breast Cancer and Moderate or Extensive Residual Cancer Burden

Source: https://onco.cc/trials/nct07721259/  
OnCo record `nct07721259` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial in triple-negative breast cancer, run by University of Washington, not yet recruiting.

## Summary

A Vaccine (STEMVAC) for Improving Survival in Patients With Triple-Negative Breast Cancer and Moderate or Extensive Residual Cancer Burden is a phase 2, randomised interventional study registered as NCT07721259 by University of Washington, with a registry enrolment figure of 60 participants, started 2026-09-30 and due to reach its primary completion in 2029-07-16. Interventions recorded: CD105/Yb-1/SOX2/CDH3/MDM2-polyepitope Plasmid DNA Vaccine; Recombinant Granulocyte-Macrophage Colony-Stimulating Factor; Biospecimen Collection. Conditions listed: Anatomic Stage I Breast Cancer AJCC v8; Anatomic Stage II Breast Cancer AJCC v8; Anatomic Stage III Breast Cancer AJCC v8; Triple-Negative Breast Carcinoma. Triple-negative eligibility wording from the registry: "* Triple-negative breast cancer as determined by the treating oncologist". Sites: United States. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: planned
- Last checked: 2026-09-24
- Tags: ctgov-ingest; tnbc-deep-dive
- Registry id: NCT07721259
- Phase: 2
- Setting: A Multiantigen Vaccine (STEMVAC) for Adjuvant Treatment of Patients With Moderate or Extensive Residual Triple-Negative Breast Cancer
- Sponsor: University of Washington
- Enrolled: 60

## Sources

- ClinicalTrials.gov NCT07721259: https://clinicaltrials.gov/study/NCT07721259

## Connected records

- cancers: [Early triple-negative breast cancer](https://onco.cc/cancers/tnbc-early/)
- terms: [Triple-negative breast cancer trials open today (registry snapshot and UK sites)](https://onco.cc/terms/tnbc-trials-open-today/)

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JSON: https://onco.cc/api/v1/entities/nct07721259.json