# A Study of Cyclophosphamide, Methotrexate, Fluorouracil (CMF) for People With Breast Cancer

Source: https://onco.cc/trials/nct07768436/  
OnCo record `nct07768436` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial of paclitaxel / nab-paclitaxel in triple-negative breast cancer, run by Memorial Sloan Kettering Cancer Center, now recruiting.

## Summary

A Study of Cyclophosphamide, Methotrexate, Fluorouracil (CMF) for People With Breast Cancer is a phase 2, interventional study registered as NCT07768436 by Memorial Sloan Kettering Cancer Center, with a registry enrolment figure of 76 participants, started 2026-08-11 and due to reach its primary completion in 2030-08-11. Interventions recorded: CMF Regimen; Paclitaxel. Conditions listed: Adenocarcinoma of the Breast; Breast Cancer; Triple Negative Breast Cancer. Triple-negative eligibility wording from the registry: "* Cohort 2 only: Patients have triple negative (ER- (10%) PR-Her 2 Neu -) in the neoadjuvant setting". Sites: United States. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-24
- Tags: ctgov-ingest; tnbc-deep-dive
- Registry id: NCT07768436
- Phase: 2
- Setting: STUDY OF DOSE DENSE CMF (Cyclophosphamide, Methotrexate, Fluorouracil) as an Alternative to AC (Doxorubicin, Cyclophosphamide) in 2 Regimens in EARLY STAGE BREAST CANCER for Patients Greater or Equal to 70
- Sponsor: Memorial Sloan Kettering Cancer Center
- Enrolled: 76

## Sources

- ClinicalTrials.gov NCT07768436: https://clinicaltrials.gov/study/NCT07768436

## Connected records

- cancers: [Early triple-negative breast cancer](https://onco.cc/cancers/tnbc-early/)
- technologies: [Cytotoxic chemotherapy](https://onco.cc/technologies/cytotoxic-chemotherapy/)
- drugs: [Paclitaxel / nab-paclitaxel](https://onco.cc/drugs/paclitaxel/)
- terms: [Triple-negative breast cancer trials open today (registry snapshot and UK sites)](https://onco.cc/terms/tnbc-trials-open-today/)

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