# Retlirafusp Alfa Plus Apatinib and Chemotherapy as Second-Line Treatment for Pancreatic Cancer

Source: https://onco.cc/trials/nct07773363/  
OnCo record `nct07773363` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial of retlirafusp alfa and rivoceranib (apatinib) in pancreatic cancer, run by Tang-Du Hospital, not yet recruiting.

## Summary

Retlirafusp Alfa Plus Apatinib and Chemotherapy as Second-Line Treatment for Pancreatic Cancer is a phase 2, interventional study registered as NCT07773363 by Tang-Du Hospital, with a registry enrolment figure of 37 participants, started 2026-08-30 and due to reach its primary completion in 2027-12-30. Interventions recorded: Retlirafusp Alfa; Apatinib; Fluoropyrimidine-Based Chemotherapy. Conditions listed: Pancreatic Cancer. Primary outcome: Progression-free survival. Pancreatic eligibility wording from the registry: "Histologically or cytologically confirmed unresectable locally advanced or metastatic pancreatic cancer". No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: planned
- Last checked: 2026-09-24
- Tags: ctgov-ingest; pancreatic-deep-dive
- Registry id: NCT07773363
- Phase: 2
- Setting: A Prospective, Open-Label, Single-Arm Clinical Study of Retlirafusp Alfa Combined With Apatinib and Chemotherapy as Second-Line Treatment for Locally Advanced or Metastatic Pancreatic Cancer
- Sponsor: Tang-Du Hospital
- Enrolled: 37

## Sources

- ClinicalTrials.gov NCT07773363: https://clinicaltrials.gov/study/NCT07773363

## Connected records

- cancers: [Locally advanced unresectable pancreatic ductal adenocarcinoma](https://onco.cc/cancers/locally-advanced-pdac/), [Metastatic pancreatic ductal adenocarcinoma](https://onco.cc/cancers/metastatic-pdac/)
- drugs: [Retlirafusp alfa](https://onco.cc/drugs/retlirafusp-alfa/), [Rivoceranib (apatinib)](https://onco.cc/drugs/rivoceranib/)
- terms: [Pancreatic cancer trials open today (registry snapshot and UK sites)](https://onco.cc/terms/pancreatic-trials-open-today/)

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