# A Prospective, Single-center, Non-randomized, Interventional Study on the Effectiveness and Safety of Combined Immunotargeted Therapy in Patients With Metastati

Source: https://onco.cc/trials/nct07809256/  
OnCo record `nct07809256` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 3 trial in lung cancer, run by EuroCityClinic LLC, now recruiting.

## Summary

A Prospective, Single-center, Non-randomized, Interventional Study on the Effectiveness and Safety of Combined Immunotargeted Therapy in Patients With Metastatic Non-small Cell Cancer With a RET Gene Translocation is a phase 3, interventional study registered as NCT07809256 by EuroCityClinic LLC, with a registry enrolment figure of 15 participants, started 2026-09 and due to reach its primary completion in 2028-08. Interventions recorded: lenvatinib pembrolizumab. Conditions listed: NSCLC (Non-small Cell Lung Cancer)R. Primary outcome: Progression-Free Survival (PFS); Objective Response Rate (ORR); Disease Control Rate (DCR). Lung eligibility wording from the registry: "Have a confirmed diagnosis of metastatic non-small cell lung cancer (NSCLC), established by examination of a tumor tissue sample, with cancer that has spread to distant parts of the body". Sites: Russia. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-25
- Also known as: LPR-2
- Tags: ctgov-ingest; lung-deep-dive
- Registry id: NCT07809256
- Phase: 3
- Setting: LPR-2: A Prospective, Single-center, Non-randomized, Interventional Study on the Effectiveness and Safety of Combined Immunotargeted Therapy in Patients With Metastatic Non-small Cell Cancer With a RET Gene Translocation
- Sponsor: EuroCityClinic LLC
- Enrolled: 15

## Sources

- ClinicalTrials.gov NCT07809256: https://clinicaltrials.gov/study/NCT07809256

## Connected records

- cancers: [Non-small-cell lung cancer](https://onco.cc/cancers/nsclc/)
- terms: [Lung cancer trials open today (registry snapshot)](https://onco.cc/terms/lung-trials-open-today/)

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