# Retlirafusp Alfa Plus Targeted Therapy and Chemotherapy for Unresectable Colorectal Liver-Limited Metastases

Source: https://onco.cc/trials/nct07815288/  
OnCo record `nct07815288` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial in colorectal cancer, run by Peking University Cancer Hospital & Institute, not yet recruiting.

## Summary

Retlirafusp Alfa Plus Targeted Therapy and Chemotherapy for Unresectable Colorectal Liver-Limited Metastases is a phase 2, interventional study registered as NCT07815288 by Peking University Cancer Hospital & Institute, with a registry enrolment figure of 80 participants, started 2026-09-30 and due to reach its primary completion in 2029-12-30. Interventions recorded: Retlirafusp alfa Combined with Targeted Therapy and Chemotherapy. Conditions listed: Colorectal Adenocarcinoma Metastatic in the Liver. Primary outcome: Objective Response Rate. Colorectal eligibility wording from the registry: "Histopathologically confirmed colorectal adenocarcinoma; liver metastasis confirmed by pathology or imaging". Sites: China. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: planned
- Last checked: 2026-09-24
- Tags: ctgov-ingest; colorectal-deep-dive
- Registry id: NCT07815288
- Phase: 2
- Setting: Retlirafusp Alfa Plus Targeted Therapy and Chemotherapy as Conversion Therapy for Initially Unresectable Colorectal Cancer Liver Metastases: An Exploratory Phase II Study
- Sponsor: Peking University Cancer Hospital & Institute
- Enrolled: 80

## Sources

- ClinicalTrials.gov NCT07815288: https://clinicaltrials.gov/study/NCT07815288

## Connected records

- cancers: [Colon cancer (adenocarcinoma of the colon)](https://onco.cc/cancers/colon-cancer/), [Rectal cancer](https://onco.cc/cancers/rectal-cancer/)
- terms: [Colorectal cancer trials open today (registry snapshot)](https://onco.cc/terms/colorectal-trials-open-today/)

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JSON: https://onco.cc/api/v1/entities/nct07815288.json