# FAPI-Guided Radiotherapy With Cadonilimab and Standard Chemotherapy for Colorectal Peritoneal Metastasis: A Phase III Randomized Controlled Trial (TORHC-PM02)

Source: https://onco.cc/trials/nct07815834/  
OnCo record `nct07815834` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 3 trial of cadonilimab in colorectal cancer, run by Fudan University, not yet recruiting.

## Summary

FAPI-Guided Radiotherapy With Cadonilimab and Standard Chemotherapy for Colorectal Peritoneal Metastasis: A Phase III Randomized Controlled Trial (TORHC-PM02) is a phase 3, randomised interventional study registered as NCT07815834 by Fudan University, with a registry enrolment figure of 198 participants, started 2026-09-01 and due to reach its primary completion in 2030-08-01. Interventions recorded: Second-Line Chemotherapy; Radiation Therapy; Cadonilimab (AK104). Conditions listed: Colon Rectal Cancer Adenocarcinoma; Peritoneal (Metastatic) Cancer; Second-line Treatment; Radiation Therapy; Immunotherapy. Primary outcome: Progression-Free Survival (PFS). Colorectal eligibility wording from the registry: "Histopathologically confirmed colorectal adenocarcinoma". Sites: China. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: planned
- Last checked: 2026-09-24
- Also known as: TORCH-PM02
- Tags: ctgov-ingest; colorectal-deep-dive
- Registry id: NCT07815834
- Phase: 3
- Setting: FAPI-Guided Hypofractionated Radiotherapy Combined With Cadonilimab and Standard Second-Line Chemotherapy Versus Standard Second-Line Chemotherapy for Peritoneal Metastasis From Colorectal Cancer: A Multicenter, Randomized, Open-Label, Phase III Trial (TORHC-PM02)
- Sponsor: Fudan University
- Enrolled: 198

## Sources

- ClinicalTrials.gov NCT07815834: https://clinicaltrials.gov/study/NCT07815834

## Connected records

- cancers: [Colon cancer (adenocarcinoma of the colon)](https://onco.cc/cancers/colon-cancer/), [Rectal cancer](https://onco.cc/cancers/rectal-cancer/)
- technologies: [Immune checkpoint inhibitors](https://onco.cc/technologies/checkpoint-inhibitor/), [IMRT / IGRT (modern external beam)](https://onco.cc/technologies/imrt-igrt/)
- drugs: [Cadonilimab](https://onco.cc/drugs/cadonilimab/)
- terms: [Colorectal cancer trials open today (registry snapshot)](https://onco.cc/terms/colorectal-trials-open-today/)

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JSON: https://onco.cc/api/v1/entities/nct07815834.json