# Toripalimab Plus Sacituzumab Tirumotecan as Neoadjuvant Therapy for Resectable NSCLC

Source: https://onco.cc/trials/nct07819578/  
OnCo record `nct07819578` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial of toripalimab and sacituzumab tirumotecan in lung cancer, run by Shaodong Hong, not yet recruiting.

## Summary

Toripalimab Plus Sacituzumab Tirumotecan as Neoadjuvant Therapy for Resectable NSCLC is a phase 2, interventional study registered as NCT07819578 by Shaodong Hong, with a registry enrolment figure of 30 participants, started 2026-10-01 and due to reach its primary completion in 2028-12-01. Interventions recorded: Toripalimab; Sacituzumab Tirumotecan (SKB264). Conditions listed: Non-Small Cell Lung Cancer. Primary outcome: Pathological Complete Response (pCR) Rate. Lung eligibility wording from the registry: "* Histologically/cytologically confirmed, treatment-naive, resectable or potentially resectable NSCLC: stage II-IIIA and selected IIIB (T3N2, T4N2) per IASLC/UICC TNM 9th edition". No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: planned
- Last checked: 2026-09-25
- Tags: ctgov-ingest; lung-deep-dive
- Registry id: NCT07819578
- Phase: 2
- Setting: A Phase II Study of Toripalimab Combined With Sacituzumab Tirumotecan as Neoadjuvant Therapy for Resectable Non-Small Cell Lung Cancer
- Sponsor: Shaodong Hong
- Enrolled: 30

## Sources

- ClinicalTrials.gov NCT07819578: https://clinicaltrials.gov/study/NCT07819578

## Connected records

- cancers: [Resectable stage I to III non-small-cell lung cancer](https://onco.cc/cancers/resectable-nsclc/)
- technologies: [Antibody-drug conjugate (ADC)](https://onco.cc/technologies/adc/), [Immune checkpoint inhibitors](https://onco.cc/technologies/checkpoint-inhibitor/)
- drugs: [Sacituzumab tirumotecan](https://onco.cc/drugs/sacituzumab-tirumotecan/), [Toripalimab](https://onco.cc/drugs/toripalimab/)
- companies: [Sichuan Kelun-Biotech](https://onco.cc/companies/kelun-biotech/)
- terms: [Lung cancer trials open today (registry snapshot)](https://onco.cc/terms/lung-trials-open-today/)

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