# Paclitaxel Polymeric Micelles Plus Ivonescimab in Recurrent or Refractory SCLC

Source: https://onco.cc/trials/nct07819591/  
OnCo record `nct07819591` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial of ivonescimab in lung cancer, run by Shaodong Hong, not yet recruiting.

## Summary

Paclitaxel Polymeric Micelles Plus Ivonescimab in Recurrent or Refractory SCLC is a phase 2, interventional study registered as NCT07819591 by Shaodong Hong, with a registry enrolment figure of 47 participants, started 2026-10-01 and due to reach its primary completion in 2028-12-01. Interventions recorded: Paclitaxel Polymeric Micelles; Ivonescimab. Conditions listed: SCLC, Recurrent. Primary outcome: Outcome Objective Response Rate (ORR) assessed by RECIST v1.1. Lung eligibility wording from the registry: "* Histologically or cytologically confirmed relapsed small-cell lung cancer after failure of platinum-based chemotherapy and PD-1/PD-L1 monoclonal antibody treatment". Sites: China. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: planned
- Last checked: 2026-09-25
- Tags: ctgov-ingest; lung-deep-dive
- Registry id: NCT07819591
- Phase: 2
- Setting: A Phase II Study of Paclitaxel Polymeric Micelles Combined With Ivonescimab in Patients With Recurrent or Refractory Small Cell Lung Cancer After Failure of Platinum-Based Chemotherapy and Anti-PD-1/PD-L1 Therapy
- Sponsor: Shaodong Hong
- Enrolled: 47

## Sources

- ClinicalTrials.gov NCT07819591: https://clinicaltrials.gov/study/NCT07819591

## Connected records

- cancers: [Small-cell lung cancer](https://onco.cc/cancers/sclc/)
- technologies: [Anti-angiogenic therapy](https://onco.cc/technologies/antiangiogenic/), [Bispecific antibodies](https://onco.cc/technologies/bispecific-antibody/), [Immune checkpoint inhibitors](https://onco.cc/technologies/checkpoint-inhibitor/)
- drugs: [Ivonescimab](https://onco.cc/drugs/ivonescimab/)
- terms: [Lung cancer trials open today (registry snapshot)](https://onco.cc/terms/lung-trials-open-today/)

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