# A Study to Evaluate INCA33890 in the Treatment of Circulating Tumor DNA-Positive Stage II/III Microsatellite Stable Colorectal Cancer After Curative Resection a

Source: https://onco.cc/trials/nct07823322/  
OnCo record `nct07823322` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial of INCA33890 in colorectal cancer, run by Incyte Corporation, not yet recruiting.

## Summary

A Study to Evaluate INCA33890 in the Treatment of Circulating Tumor DNA-Positive Stage II/III Microsatellite Stable Colorectal Cancer After Curative Resection and Chemotherapy is a phase 2, interventional study registered as NCT07823322 by Incyte Corporation, with a registry enrolment figure of 40 participants, started 2026-10-26 and due to reach its primary completion in 2029-05-14. Interventions recorded: INCA33890. Conditions listed: CRC (Colorectal Cancer). Primary outcome: Circulating tumor DNA (ctDNA) clearance. Colorectal eligibility wording from the registry: "* Received curative-intent (R0) resection of histologically confirmed Stage II or III colorectal adenocarcinoma". No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: planned
- Last checked: 2026-09-24
- Also known as: NEXERA-204
- Tags: ctgov-ingest; colorectal-deep-dive
- Registry id: NCT07823322
- Phase: 2
- Setting: A Phase 2 Study of INCA33890 in the Treatment of Circulating Tumor DNA-Positive Stage II/III Microsatellite Stable Colorectal Cancer After Curative Resection and Chemotherapy (NEXERA-204)
- Sponsor: Incyte Corporation
- Enrolled: 40

## Sources

- ClinicalTrials.gov NCT07823322: https://clinicaltrials.gov/study/NCT07823322

## Connected records

- cancers: [Colon cancer (adenocarcinoma of the colon)](https://onco.cc/cancers/colon-cancer/), [Rectal cancer](https://onco.cc/cancers/rectal-cancer/)
- technologies: [MRD / molecular residual disease testing](https://onco.cc/technologies/mrd-testing/)
- drugs: [INCA33890](https://onco.cc/drugs/inca33890/)
- companies: [Incyte](https://onco.cc/companies/incyte/)
- terms: [Colorectal cancer trials open today (registry snapshot)](https://onco.cc/terms/colorectal-trials-open-today/)

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