# Local Methylene Blue Injection for Prevention of Anastomotic Leakage and Permanent Stoma After Low Anterior Resection for Rectal Cancer

Source: https://onco.cc/trials/nct07833319/  
OnCo record `nct07833319` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial in colorectal cancer, run by Peking University Cancer Hospital & Institute, now recruiting.

## Summary

Local Methylene Blue Injection for Prevention of Anastomotic Leakage and Permanent Stoma After Low Anterior Resection for Rectal Cancer is a phase 2, interventional study registered as NCT07833319 by Peking University Cancer Hospital & Institute, with a registry enrolment figure of 26 participants, started 2025-11-25 and due to reach its primary completion in 2027-07-01. Interventions recorded: methylene blue injection. Conditions listed: Rectal Cancers. Primary outcome: Proportion of participants with successful stoma closure within 12 months after surgery. Colorectal eligibility wording from the registry: "Adults aged 18 years or older with histologically confirmed rectal adenocarcinoma". Sites: China. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-24
- Also known as: PKUCH-R10
- Tags: ctgov-ingest; colorectal-deep-dive
- Registry id: NCT07833319
- Phase: 2
- Setting: A Prospective Single-arm Phase II Clinical Study Evaluating Local Methylene Blue Injection for Prevention of Anastomotic Leakage and Permanent Stoma in High-risk Patients With Rectal Cancer Undergoing Low Anterior Resection
- Sponsor: Peking University Cancer Hospital & Institute
- Enrolled: 26

## Sources

- ClinicalTrials.gov NCT07833319: https://clinicaltrials.gov/study/NCT07833319

## Connected records

- cancers: [Rectal cancer](https://onco.cc/cancers/rectal-cancer/)
- terms: [Colorectal cancer trials open today (registry snapshot)](https://onco.cc/terms/colorectal-trials-open-today/)

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