# CR-002 in Adult Participants With Locally Advanced or Metastatic Solid Tumors

Source: https://onco.cc/trials/nct07909031/  
OnCo record `nct07909031` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 1/2 trial of CR-002 run by Crescent Biopharma, Inc., now recruiting.

## Summary

CR-002 in Adult Participants With Locally Advanced or Metastatic Solid Tumors is a phase 1/2 interventional study registered as NCT07909031 by Crescent Biopharma, Inc., with 219 participants planned, started 2026-10-21. Conditions recorded: Head and Neck Squamous Cell Carcinoma (HNSCC) - Recurrent/Metastatic (R/M), Gastric/GEJ, Biliary Tract Cancer (BTC), Esophageal Squamous Cell Carcinoma (ESCC), Ovarian Cancer, Endometrial Cancer, Cervical Cancer Metastatic and Non-small Cell Lung Cancer (NSCLC). Interventions recorded: CR-002.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-11-03
- Tags: pipeline; ctgov-ingest
- Registry id: NCT07909031
- Phase: 1/2
- Setting: A Phase 1/2, Multicenter, Open-label, Dose Escalation and Dose Expansion Study to Evaluate the Safety, Pharmacokinetics, and Antitumor Activity of CR-002 in Adult Participants With Locally Advanced or Metastatic Solid Tumors
- Sponsor: Crescent Biopharma, Inc.
- Enrolled: 219

## Sources

- ClinicalTrials.gov NCT07909031: https://clinicaltrials.gov/study/NCT07909031

## Connected records

- cancers: [Biliary tract cancer (all types)](https://onco.cc/cancers/biliary-tract-cancer/), [Endometrial cancer](https://onco.cc/cancers/endometrial/), [Gastric & gastro-oesophageal junction cancer](https://onco.cc/cancers/gastric/), [Head and neck squamous cell carcinoma](https://onco.cc/cancers/head-and-neck/), [Metastatic cancer (cancer that has spread)](https://onco.cc/cancers/metastatic-cancer/), [Non-small-cell lung cancer](https://onco.cc/cancers/nsclc/), [Oesophageal squamous cell carcinoma](https://onco.cc/cancers/oesophageal-squamous-cell-carcinoma/), [Ovarian cancer](https://onco.cc/cancers/ovarian/)
- drugs: [CR-002](https://onco.cc/drugs/cr-002/)
- companies: [Crescent Biopharma](https://onco.cc/companies/crescent-biopharma/)

---
JSON: https://onco.cc/api/v1/entities/nct07909031.json