# Singapore limb cryocompression expansion study

Source: https://onco.cc/trials/nuh-limb-cryocompression-expansion/  
OnCo record `nuh-limb-cryocompression-expansion` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A Singapore study that builds on the earlier safety work with a cooling-and-compression device for the hands and feet, now in 200 patients.

## Summary

The National University Hospital, Singapore, group that published a safety series of continuous-flow limb cryocompression (13 patients, 142 cycles, no grade 2 or worse neuropathy) is running an expansion study of the Paxman Limb Cryocompression System with an estimated 200 participants. Its earlier studies are NCT03299582 and NCT05095051.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-11-04
- Also known as: A Novel Limb Cryocompression System for Prevention of Chemotherapy Induced Peripheral Neuropathy - Expansion Study
- Tags: machines-wave3
- Registry id: NCT05606068
- Phase: not-applicable
- Setting: Patients receiving neurotoxic chemotherapy, using the Paxman Limb Cryocompression System
- Sponsor: National University Hospital, Singapore
- Enrolled: 200

## Sources

- ClinicalTrials.gov NCT05606068: https://clinicaltrials.gov/study/NCT05606068
- Bandla et al., safety of continuous-flow limb cryocompression in 13 patients (Support Care Cancer 2020): https://doi.org/10.1007/s00520-019-05177-2
- ClinicalTrials.gov NCT03299582: https://clinicaltrials.gov/study/NCT03299582
- ClinicalTrials.gov NCT05095051: https://clinicaltrials.gov/study/NCT05095051

## Connected records

- technologies: [Limb cryocompression devices for chemotherapy nerve damage (Paxman Neuropathy System, Hilotherm ChemoCare)](https://onco.cc/technologies/limb-cryocompression-devices/)
- companies: [Paxman](https://onco.cc/companies/paxman/)

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