# NUTM2B

Source: https://onco.cc/targets/nutm2b/  
OnCo record `nutm2b` (Target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

NUTM2B (NUT family member 2B) is a gene. In the public catalogues the evidence so far is association rather than a proven role. Tied to Sarcomas.

## Summary

UniProt has no function text for A6NNL0; HGNC names it "NUT family member 2B".

Open Targets scores its association with cancer at 0.61 (direct and indirect evidence; datatypes literature 0.70, genetic association 0.00, somatic mutation 0.97).

## Fields

- Kind: Target
- Last checked: 2026-09-23
- Also known as: NUT family member 2B; bA119F19.1; FAM22B
- Tags: cancer-genes-wave
- Symbol: NUTM2B
- Class: other
- Biology: UniProt has no function text for A6NNL0; HGNC names it "NUT family member 2B". Locus 10q22.3 (HGNC).
- Where found: Sarcomas: Open Targets association 0.58 with sarcoma (MONDO_0005089)

## Notes

- Written by scripts/fetch-cancer-genes.ts from CIViC, Open Targets, IntOGen, HGNC and UniProt; the function text is UniProt's, condensed and in UK spelling. Roles: none stated by the sources. Evidence tier "association-only" is the strongest of those signals.
- Prevalence not recorded: none of the sources gives a positivity rate.

## Sources

- HGNC HGNC:23445: https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:23445
- UniProt A6NNL0: https://www.uniprot.org/uniprotkb/A6NNL0/entry
- NCBI Gene 729262: https://www.ncbi.nlm.nih.gov/gene/729262
- Ensembl ENSG00000188199: https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000188199

## Connected records

- collections: [Open Targets Platform](https://onco.cc/collections/open-targets/)
- cancers: [Sarcomas (soft tissue, bone, GIST)](https://onco.cc/cancers/sarcoma/)

---
JSON: https://onco.cc/api/v1/entities/nutm2b.json