# Oncotherapy Solutions

Source: https://onco.cc/companies/oncotherapy-solutions/  
OnCo record `oncotherapy-solutions` (Company). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

Oncotherapy Solutions is a Seattle company developing peptide drug conjugates: small peptides that carry a cell-killing drug to tumour cells. Its lead, OTS-P22, is being prepared for triple-negative breast cancer.

## Summary

Oncotherapy Solutions, LLC develops peptide drug conjugates and bispecific drug conjugates for drug-resistant and metastatic solid tumours. Its most advanced preclinical candidate, OTS-P22, targets a receptor that the company says is highly expressed in many solid tumours; the company reports that a single intravenous dose inhibited tumour growth in an HCC1806 triple-negative breast cancer mouse model, and plans IND-enabling studies for triple-negative breast, metastatic ovarian and endometrial cancers. A 2026 National Cancer Institute SBIR award funds a lead peptide drug conjugate for triple-negative breast cancer; its abstract describes conjugates aimed at the luteinising hormone-releasing hormone receptor.

## Fields

- Kind: Company
- Last checked: 2026-11-04
- Also known as: Oncotherapy Solutions, LLC
- HQ: Seattle, WA
- Type: biotech
- Website: https://oncotherapysolutions.com/

## Notes

- Company website (home and pipeline pages) and the NIH RePORTER record read on 4 November 2026. The website does not name the receptor OTS-P22 targets; the award abstract describes LHRH receptor conjugates, and whether OTS-P22 is one of them is not stated.

## Sources

- Official website: https://oncotherapysolutions.com/
- Pipeline: https://oncotherapysolutions.com/pipeline
- NIH RePORTER: award 1R43CA306418-01A1: https://reporter.nih.gov/project-details/11402095

## Connected records

- cancers: [Triple-negative breast cancer (TNBC)](https://onco.cc/cancers/tnbc/)
- fronts: [Antibody-Drug Conjugates](https://onco.cc/fronts/adcs/), [Targeted Therapy](https://onco.cc/fronts/targeted-therapy/)
- technologies: [Peptide-drug & small-molecule-drug conjugates](https://onco.cc/technologies/peptide-drug-conjugate/)
- drugs: [OTS-P22](https://onco.cc/drugs/ots-p22/)

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