# Otsuka Pharmaceutical

Source: https://onco.cc/companies/otsuka/  
OnCo record `otsuka` (Company). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

Otsuka is a Japanese pharmaceutical group whose oncology portfolio centres on haematology: intravenous busulfan (Busulfex) and decitabine (Dacogen).

## Summary

Otsuka Pharmaceutical, part of Otsuka Holdings, is best known for CNS medicines but markets Busulfex (busulfan) for transplant conditioning and Dacogen (decitabine) for myelodysplastic syndromes in the US, and Dacogen for elderly acute myeloid leukaemia in Europe through Janssen. It also develops Lonsurf outside Japan with Taiho, a group company.

## Fields

- Kind: Company
- Last checked: 2026-09-10
- Also known as: Astex Pharmaceuticals; Graceway Pharmaceuticals, LLC; Graceway Pharmaceuticals
- HQ: Tokyo
- Type: pharma
- Website: https://www.otsuka.co.jp/en/
- Ticker: 4578.T

## Sources

- Official website: https://www.otsuka.co.jp/en/

## Connected records

- cancers: [Acute myeloid leukaemia](https://onco.cc/cancers/aml/), [Myelodysplastic syndromes / neoplasms (MDS)](https://onco.cc/cancers/mds/)
- drugs: [Busulfan](https://onco.cc/drugs/busulfan/), [Decitabine](https://onco.cc/drugs/decitabine/), [Trifluridine/tipiracil](https://onco.cc/drugs/trifluridine-tipiracil/)
- companies: [Johnson & Johnson](https://onco.cc/companies/johnson-johnson/), [Taiho Pharmaceutical (Otsuka)](https://onco.cc/companies/taiho/)
- trials: [A Phase I/II Study of OJP-001 in Patients With Adult T-cell Leukemia/Lymphoma](https://onco.cc/trials/nct07075328/), [A Study Comparing Treatment Preference Between Oral Decitabine/Cedazuridine and Azacitidine in Myelodysplastic Syndrome, Low-Blast Acute Myeloid Leukemia, or Chronic Myelomonocytic Leukemia](https://onco.cc/trials/nct05883956/), [The Study for CML Who Failed Prior TKIs or With T315I Mutation or Ph+ ALL Who Failed Prior TKIs or With T315I Mutation](https://onco.cc/trials/nct04233346/)

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JSON: https://onco.cc/api/v1/entities/otsuka.json