# The Ottawa Hospital Cancer Centre / Ottawa Hospital Research Institute

Source: https://onco.cc/institutions/ottawa-hospital/  
OnCo record `ottawa-hospital` (Institution). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

Ottawa's academic cancer centre, a world leader in oncolytic viruses (John Bell), the first made-in-Canada CAR-T trial and pragmatic REaCT trials.

## Summary

The Ottawa Hospital Cancer Centre and the Ottawa Hospital Research Institute (OHRI) form eastern Ontario's academic cancer programme with the University of Ottawa. John Bell's laboratory is one of the world's leading oncolytic virus groups, developing the Maraba MG1 and vaccinia platforms and co-founding Turnstone Biologics; Rebecca Auer studies perioperative immunotherapy to prevent metastasis after surgery. Natasha Kekre led CLIC-01, the first clinical trial of a CAR-T product manufactured in Canada, and the Rethinking Clinical Trials (REaCT) programme, led by Mark Clemons and Dean Fergusson, embeds pragmatic randomised trials into routine cancer care. The centre also hosts a large radiation oncology and haematology service.

## Fields

- Kind: Institution
- Last checked: 2026-09-09
- Also known as: OHRI; TOH Cancer Centre
- City: Ottawa, ON, CA
- Type: hospital
- Website: https://www.ottawahospital.on.ca

## Sources

- The Ottawa Hospital cancer program: https://www.ottawahospital.on.ca/en/clinical-services/deptpgrmcs/programs/cancer-program/
- Ottawa Hospital Research Institute: https://www.ohri.ca

## Connected records

- cancers: [Colorectal cancer](https://onco.cc/cancers/colorectal/), [Diffuse large B-cell lymphoma](https://onco.cc/cancers/dlbcl/), [HR-positive / HER2-negative breast cancer](https://onco.cc/cancers/breast-hr-positive/)
- technologies: [CAR-T cell therapy](https://onco.cc/technologies/car-t/), [Oncolytic viruses](https://onco.cc/technologies/oncolytic-virus/)
- companies: [Canadian Cancer Trials Group (CCTG)](https://onco.cc/companies/cctg/)
- terms: [Real-world evidence](https://onco.cc/terms/real-world-evidence/)
- people: [John C. Bell](https://onco.cc/people/john-bell/), [Rebecca Auer](https://onco.cc/people/rebecca-auer/)
- bottlenecks: [Manufacturing cost and time for living and radioactive medicines](https://onco.cc/bottlenecks/b-manufacturing-cell-therapy/), [Trial design, endpoints and cost](https://onco.cc/bottlenecks/b-trial-design/), [Trials enrol too few, too slowly](https://onco.cc/bottlenecks/b-trial-enrolment/)
- institutions: [Ontario Health (Cancer Care Ontario)](https://onco.cc/institutions/ontario-health-cancer-care-ontario/)

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