# PAN study (Owlstone breath test for several cancers)

Source: https://onco.cc/trials/pan-owlstone/  
OnCo record `pan-owlstone` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A UK study testing whether a breath test can tell people with stomach, gullet or liver cancer from people without.

## Summary

PAN study (NCT03756597) is an observational study sponsored by Owlstone Ltd with Cambridge University Hospitals NHS Foundation Trust, Cancer Research UK. It is a case-control study of whether Breath Biopsy can distinguish patients with and without different cancers by breath biomarkers.

The registry record, read on 29 October 2026, gives its status as completed, with 268 participants enrolled, a start on 26 September 2018 and primary completion on 2 December 2022.

## Fields

- Kind: Trial
- Status: completed
- Last checked: 2026-10-29
- Also known as: PAN-study; Pan-Cancer Early Detection Study
- Registry id: NCT03756597
- Phase: observational
- Setting: Patients with gastric, oesophageal or liver cancer and controls at Cambridge University Hospitals, giving breath samples
- Sponsor: Owlstone Ltd with Cambridge University Hospitals NHS Foundation Trust, Cancer Research UK
- Enrolled: 268

## Sources

- ClinicalTrials.gov NCT03756597: https://clinicaltrials.gov/study/NCT03756597

## Connected records

- fronts: [Early Detection & Screening](https://onco.cc/fronts/early-detection/)
- technologies: [Breath and volatile-organic-compound detection](https://onco.cc/technologies/breath-vocs/), [Liquid biopsy (ctDNA)](https://onco.cc/technologies/liquid-biopsy/), [Multi-cancer early detection (MCED)](https://onco.cc/technologies/mced/)
- companies: [Owlstone Medical](https://onco.cc/companies/owlstone-medical/)
- institutions: [Cancer Research UK](https://onco.cc/institutions/cruk/)

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JSON: https://onco.cc/api/v1/entities/pan-owlstone.json